July 1, 2025 Scott Kirkland Chief Financial Officer Ecolab, Inc. 1 Ecolab Place St. Paul, MN 55102 Re: Ecolab, Inc. Form 10-K for the fiscal year ended December 31, 2024 Filed February 21, 2025 File No. 001-09328 Dear Scott Kirkland: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services