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S-3 424B5 EX-FILING FEES 333-270272-01 0000064670 MEDTRONIC INC N/A N/A The prospectus is not a final prospectus for the related offering. 0000064670 2025-09-15 2025-09-15 0000064670 1 2025-09-15 2025-09-15 0000064670 2 2025-09-15 2025-09-15 0000064670 3 2025-09-15 2025-09-15 0000064670 4 2025-09-15 2025-09-15 0000064670 5 2025-09-15 2025-09-15 0000064670 6 2025-09-15 2025-09-15 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

MEDTRONIC INC

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Debt 2.950% Senior Notes Due 2030 457(r) 881,925,000 $ 881,695,699.50 0.0001531 $ 134,988.00
Fees to be Paid 2 Debt Guarantee of Medtronic Public Limited Company of 2.950% Senior Notes Due 2030 Other 0.0001531 $ 0.00
Fees to be Paid 3 Debt Guarantee of Medtronic Global Holdings S.C.A. of 2.950% Senior Notes Due 2030 Other 0.0001531 $ 0.00
Fees to be Paid 4 Debt 4.200% Senior Notes Due 2045 457(r) 881,925,000 $ 881,016,617.25 0.0001531 $ 134,884.00
Fees to be Paid 5 Debt Guarantee of Medtronic Public Limited Company of 4.200% Senior Notes Due 2045 Other 0.0001531 $ 0.00
Fees to be Paid 6 Debt Guarantee of Medtronic Global Holdings S.C.A. of 4.200% Senior Notes Due 2045 Other 0.0001531 $ 0.00
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 1,762,712,316.75

$ 269,872.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 269,872.00

Offering Note

1

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering.

2

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering. (3) Pursuant to Rule 457(n) under the Securities Act of 1933, as amended, no separate registration fee is payable for the guarantees.

3

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering. (3) Pursuant to Rule 457(n) under the Securities Act of 1933, as amended, no separate registration fee is payable for the guarantees.

4

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering.

5

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering. (3) Pursuant to Rule 457(n) under the Securities Act of 1933, as amended, no separate registration fee is payable for the guarantees.

6

(1) The U.S. dollar equivalent of the Amount Registered has been calculated using a euro/U.S. dollar exchange rate of euro1.00 = U.S. $1.1759, as announced by the U.S. Federal Reserve Board as of September 5, 2025. (2) The filing fee is calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended. The prospectus supplement to which this exhibit is attached is a final prospectus for the related offering. (3) Pursuant to Rule 457(n) under the Securities Act of 1933, as amended, no separate registration fee is payable for the guarantees.
Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A