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						Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the following Registration Statements:

(1)    Registration Statements on Form S-3 No. 333-233377 and No. 333-268327 of Cardinal Health, Inc.,

(2)    Registration Statements on Form S-4 No. 333-62938 and No. 333-74761 of Cardinal Health, Inc., and

(3)    Registration Statements on Form S-8:

S-8 Registration Number			Description
33-42357			Cardinal Distribution, Inc. Profit Sharing and Retirement Savings Plan
333-90423			Cardinal Health, Inc. Incentive Deferred Compensation Plan, As Amended
333-38192			Cardinal Health, Inc. Outside Directors Equity Incentive Plan
333-38198			Cardinal Health, Inc. Profit Sharing and Retirement Savings Plan, As Amended
333-56010			Cardinal Health, Inc. Profit Sharing, Retirement and Savings Plan for Employees of Puerto Rico
333-129725			Cardinal Health, Inc. 2005 Long-Term Incentive Plan
333-149107			Cardinal Health Deferred Compensation Plan, as amended and restated effective January 1, 2005
			Cardinal Health 401(k) Savings Plan (as amended and restated January 1, 2006)
			Cardinal Health 401(k) Savings Plan For Employees of Puerto Rico (as amended and restated January 1, 2005)
			Syncor International Corporation Employees’ Savings and Stock Ownership Plan, as amended and restated effective January 1, 1997
333-155156			Cardinal Health, Inc. 2005 Long-Term Incentive Plan, (As Amended and Restated as of November 5, 2008)
333-163128			Cardinal Health, Inc. 2005 Long-Term Incentive Plan
			Cardinal Health, Inc. 2007 Nonemployee Directors Equity Plan
333-164736			Cardinal Health Deferred Compensation Plan, as amended and restated effective January 1, 2009 (as amended)
			Cardinal Health 401(k) Savings Plan, as amended and restated January 1, 2006 (as amended)
333-177728			Cardinal Health, Inc. 2011 Long-Term Incentive Plan
333-183471			Cardinal Health Deferred Compensation Plan
			Cardinal Health 401(k) Savings Plan
333-206339			Cardinal Health Deferred Compensation Plan
			Cardinal Health 401(k) Savings Plan
			Cardinal Health 401(k) Savings Plan for Employees of Puerto Rico
333-206340			Cardinal Health, Inc. 2011 Long-Term Incentive Plan

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						Exhibit 23.1

333-214412			Amended Cardinal Health, Inc. 2011 Long-Term Incentive Plan
333-219892			Cardinal Health Deferred Compensation Plan
			Cardinal Health 401(k) Savings Plan
			Cardinal Health 401(k) Savings Plan for Employees of Puerto Rico
333-233380			Cardinal Health Deferred Compensation Plan
			Cardinal Health 401(k) Savings Plan
			Cardinal Health 401(k) Savings Plan for Employees of Puerto Rico
333-260921			Cardinal Health, Inc. 2021 Long-Term Incentive Plan, As Amended
333-268236			Cardinal Health 401(k) Savings Plan
			Cardinal Health 401(k) Savings Plan for Employee of Puerto Rico

of our reports dated August 14, 2024, with respect to the consolidated financial statements and schedule of Cardinal Health, Inc. and subsidiaries and the effectiveness of internal control over financial reporting of Cardinal Health, Inc. and subsidiaries, included in this Annual Report (Form 10-K) of Cardinal Health, Inc. and subsidiaries for the year ended June 30, 2024.

/s/ Ernst & Young LLP
Grandview Heights, Ohio
August 14, 2024