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Preliminary—Subject to Completion SCAN TO VIEW MATERIALS & VOTE w BIOLIFE SOLUTIONS, INC. VOTE BY INTERNET C/O BROADRIDGE CORPORATE ISSUER SOLUTIONS, INC. Before The Meeting—Go to www.proxyvote.com or scan the QR Barcode above P.O. BOX 1342 BRENTWOOD, NY 11717 Use the Internet to transmit your voting instructions and for electronic delivery of information up until 11:59 p.m. Eastern Time on [TBD], 2026. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction form. During The Meeting—Go to www.virtualshareholdermeeting.com/BLFS2026SM You may attend the meeting via the Internet and vote during the meeting. Have the information that is printed in the box marked by the arrow available and follow the instructions. VOTE BY PHONE—1-800-690-6903 Use any touch-tone telephone to transmit your voting instructions up until 11:59 p.m. Eastern Time on [TBD], 2026. Have your proxy card in hand when you call and then follow the instructions. VOTE BY MAIL Mark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, c/o Broadridge, 51 Mercedes Way, Edgewood, NY 11717. TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS: T03158-TBD KEEP THIS PORTION FOR YOUR RECORDS THIS PROXY CARD IS VALID ONLY WHEN SIGNED AND DATED. DETACH AND RETURN THIS PORTION ONLY BIOLIFE SOLUTIONS, INC. Preliminary—Subject to Completion The Board of Directors recommends you vote FOR proposals 1, 2 and 3: For Against Abstain 1. To adopt the Agreement and Plan of Merger, dated July 21, 2026 (such agreement, as it may be amended, modified or supplemented from time to time, the “Merger Agreement”), by and among BioLife Solutions, Inc., a Delaware corporation (“BioLife”), Repligen Corporation, a Delaware corporation ! ! ! (“Repligen”), Bravo Merger Sub I, Inc., a Delaware corporation and wholly owned subsidiary of Repligen (“Merger Sub 1”) and Bravo Merger Sub II, LLC, a Delaware limited liability company and wholly owned subsidiary of Repligen (“Merger Sub 2”), pursuant to which, and subject to the satisfaction or waiver of the conditions specified therein, Merger Sub 1 will be merged with and into BioLife (the “First Merger”), with BioLife surviving the First Merger as a direct, wholly owned subsidiary of Repligen (the “Surviving Company”), and immediately following the First Merger, the Surviving Company will be merged with and into Merger Sub 2 (the “Second Merger,” and, together with the First Merger, the “Mergers”), with Merger Sub 2 surviving the Second Merger as a direct, wholly owned subsidiary of Repligen. 2. To approve, on a non-binding, advisory basis, the compensation that may be paid or become payable to BioLife’s named executive officers that is based ! ! ! on or otherwise related to the Merger Agreement and the transactions contemplated thereby. 3. To adjourn the special meeting of the BioLife stockholders (the “Special Meeting”) to a later date or dates, if necessary or appropriate, including to solicit ! ! ! additional proxies to approve the proposal to adopt the Merger Agreement if there are insufficient votes to adopt the Merger Proposal at the time of the Special Meeting. NOTE: In their discretion, the proxies are authorized to vote upon such other business that may properly come before the Special Meeting or any adjournments or postponements thereof. Please sign exactly as your name(s) appear(s) hereon. When signing as attorney, executor, administrator, or other fiduciary, please give full title as such. Joint owners should each sign personally. All holders must sign. If a corporation or partnership, please sign in full corporate or partnership name by authorized officer. Signature [PLEASE SIGN WITHIN BOX] Date Signature (Joint Owners) Date
