X0306 4 2018-04-16 0000811212 CESCA THERAPEUTICS INC. KOOL 0001669923 Li Yishu 2711 CITRUS ROAD RANCHO CORDOVA CA 95742 1 Second Amended and Restated Convertible Promissory Note 1.61 2018-04-16 4 A 0 10000000 1.61 A 2018-04-16 2022-03-06 Common Stock, par value $.001 per share 6211180 10000000 I By Spouse through Boyalife Asset Holding II, Inc. The Second Amended and Restated Convertible Promissory Note due March 6, 2022 (the "Note") was issued pursuant to a First Amended and Restated Revolving Credit Agreement, dated April 16, 2018, as reported in the Issuer's Form 8-K filed on April 18, 2018. The Note is in the maximum aggregate principal amount of $10.0 million, and the outstanding balance and accrued but unpaid interest is convertible at any time by the holder thereof at an initial conversion price of $1.61 per share, subject to adjustment as set forth in the Note. The reported securities are held directly by Boyalife Asset Holding II, Inc. The reporting person is the spouse of Dr. Xiaochun Xu, who is the sole owner and officer of Boyalife Group, Inc., which in turn is the sole owner of Boyalife Asset Holding II, Inc. As such, the reporting person may be deemed to have a pecuniary interest in the securities reported herein and owned directly by Boyalife Asset Holding II, Inc. The reporting person disclaims beneficial ownership of such securities, and this report shall not be deemed an admission that such reporting person is the beneficial owner of the securities for the purpose of Section 16 or for any other purpose, except to the extent of such reporting person's pecuniary interest therein. /s/ Yishu Li 2018-04-18