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F-3 424B5 EX-FILING FEES 333-271955 0000891478 Banco Santander, S.A. N/A N/A The prospectus is not a final prospectus for the related offering. 0000891478 2025-10-31 2025-10-31 0000891478 1 2025-10-31 2025-10-31 0000891478 2 2025-10-31 2025-10-31 0000891478 3 2025-10-31 2025-10-31 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

F-3

Banco Santander, S.A.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Debt Senior Non Preferred Floating Rate Notes Due 2030 457(r) $ 300,000,000.00 0.0001381 $ 41,430.00
Fees to be Paid 2 Debt 4.551% Senior Non Preferred Fixed Rate Notes Due 2030 457(r) $ 1,250,000,000.00 0.0001381 $ 172,625.00
Fees to be Paid 3 Debt 5.127% Senior Non Preferred Fixed Rate Notes Due 2035 457(r) $ 1,250,000,000.00 0.0001381 $ 172,625.00
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 2,800,000,000.00

$ 386,680.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 386,680.00

Offering Note

1

(1) Calculated in accordance with Rule 457(r) under the U.S. Securities Act of 1933, as amended (the "Securities Act"). (2) Determined in accordance with Section 6(b) of the Securities Act at a rate equal to $138.10 per $1,000,000 of the proposed maximum aggregate offering price.

2

(1) Calculated in accordance with Rule 457(r) under the U.S. Securities Act of 1933, as amended (the "Securities Act"). (2) Determined in accordance with Section 6(b) of the Securities Act at a rate equal to $138.10 per $1,000,000 of the proposed maximum aggregate offering price.

3

(1) Calculated in accordance with Rule 457(r) under the U.S. Securities Act of 1933, as amended (the "Securities Act"). (2) Determined in accordance with Section 6(b) of the Securities Act at a rate equal to $138.10 per $1,000,000 of the proposed maximum aggregate offering price.
Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A