September 6, 2024 Larry J. Helling Chief Executive Officer and Director QCR Holdings, Inc. 3551 Seventh Street Moline, IL 61265 Re: QCR Holdings, Inc. Definitive Proxy Statement on Schedule 14A Filed April 8, 2024 File No. 000-22208 Dear Larry J. Helling: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Disclosure Review Program