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UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100   18,497,360 136,000 SH   OTR   136,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   191,825,919 5,767,466 SH   OTR   5,767,466 0 0
AKERO THERAPEUTICS INC COM 00973Y108   213,440 4,000 SH   OTR   4,000 0 0
ALEANNA INC *W EXP 12/13/202 01444V111   232,650 990,000 SH   OTR   990,000 0 0
ALEANNA INC COM CL A 01444V103   49,761 78,400 SH   OTR   78,400 0 0
ALKERMES PLC SHS G01767105   19,788,478 691,663 SH   OTR   691,663 0 0
ALPHABET INC CAP STK CL C 02079K107   312,532,798 1,761,840 SH   OTR   1,761,840 0 0
ALTIMMUNE INC COM NEW 02155H200   106,812 27,600 SH   OTR   27,600 0 0
ALVOTECH ORDINARY SHARES L01800108   1,821,036 199,675 SH   OTR   199,675 0 0
AMAZON COM INC COM 023135106   665,760,894 3,034,600 SH   OTR   3,034,600 0 0
AMICUS THERAPEUTICS INC COM 03152W109   91,680 16,000 SH   OTR   16,000 0 0
ANALOG DEVICES INC COM 032654105   302,809,044 1,272,200 SH   OTR   1,272,200 0 0
ANSYS INC COM 03662Q105   350,211,296 997,128 SH   OTR   997,128 0 0
AON PLC SHS CL A G0403H108   708,674,129 1,986,417 SH   OTR   1,986,417 0 0
ARAMARK COM 03852U106   540,110,481 12,899,701 SH   OTR   12,899,701 0 0
ARCELLX INC COMMON STOCK 03940C100   263,400 4,000 SH   OTR   4,000 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   364,520 26,000 SH   OTR   26,000 0 0
ARDELYX INC COM 039697107   90,160 23,000 SH   OTR   23,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   249,640 15,800 SH   OTR   15,800 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   241,640 1,400 SH   OTR   1,400 0 0
AUTODESK INC COM 052769106   540,091,920 1,744,652 SH   OTR   1,744,652 0 0
AXSOME THERAPEUTICS INC COM 05464T104   417,560 4,000 SH   OTR   4,000 0 0
AZEK CO INC CL A 05478C105   170,735,090 3,141,400 SH   OTR   3,141,400 0 0
BEAM THERAPEUTICS INC COM 07373V105   170,323,018 10,013,111 SH   OTR   10,013,111 0 0
BEONE MEDICINES LTD SPONSORED ADS 07725L102   266,277 1,100 SH   OTR   1,100 0 0
BETA BIONICS INC COM 08659B102   61,209,075 4,203,920 SH   OTR   4,203,920 0 0
BEYOND MEAT INC COM 08862E109   66,310 19,000 SH   OTR   19,000 0 0
BIODESIX INC COM 09075X108   36,122 128,000 SH   OTR   128,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107   427,605,332 3,981,057 SH   OTR   3,981,057 0 0
BRIDGEBIO PHARMA INC COM 10806X102   341,122,000 7,900,000 SH   OTR   7,900,000 0 0
BRIGHTSPRING HEALTH SVCS INC COM 10950A106   518,980 22,000 SH   OTR   22,000 0 0
BRUKER CORP COM 116794108   206,000 5,000 SH   OTR   5,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107   40,040 28,000 SH   OTR   28,000 0 0
CANOPY GROWTH CORP COM NEW 138035704   36,600 30,000 SH   OTR   30,000 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309   407,130 41,000 SH   OTR   41,000 0 0
CARDINAL HEALTH INC COM 14149Y108   76,272,000 454,000 SH   OTR   454,000 0 0
CBRE GROUP INC CL A 12504L109   296,092,897 2,113,138 SH   OTR   2,113,138 0 0
CENCORA INC COM 03073E105   299,850 1,000 SH   OTR   1,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   59,515,239 4,529,318 SH   OTR   4,529,318 0 0
CG ONCOLOGY INC COM 156944100   208,000 8,000 SH   OTR   8,000 0 0
CHAMPIONX CORPORATION COM 15872M104   105,445,800 4,245,000 SH   OTR   4,245,000 0 0
CIDARA THERAPEUTICS INC COM NEW 171757206   9,742,000 200,000 SH   OTR   200,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201   122,060 17,000 SH   OTR   17,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   133,621,778 4,646,098 SH   OTR   4,646,098 0 0
DISNEY WALT CO COM 254687106   604,457,975 4,874,268 SH   OTR   4,874,268 0 0
DYNE THERAPEUTICS INC COM 26818M108   95,200 10,000 SH   OTR   10,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106   16,044,301 2,122,262 SH   OTR   2,122,262 0 0
ENCOMPASS HEALTH CORP COM 29261A100   86,822,040 708,000 SH   OTR   708,000 0 0
EVOLENT HEALTH INC CL A 30050B101   157,640 14,000 SH   OTR   14,000 0 0
EXELIXIS INC COM 30161Q104   706,764,663 16,035,500 SH   OTR   16,035,500 0 0
FLUTTER ENTMT PLC SHS G3643J108   51,787,999 181,229 SH   OTR   181,229 0 0
FULL TRUCK ALLIANCE CO LTD SPONSORED ADS 35969L108   18,312,562 1,550,598 SH   OTR   1,550,598 0 0
GE HEALTHCARE TECHNOLOGIES I COMMON STOCK 36266G107   97,920,540 1,322,000 SH   OTR   1,322,000 0 0
GENEDX HOLDINGS CORP COM CL A 81663L200   30,155,554 326,677 SH   OTR   326,677 0 0
GERON CORP COM 374163103   60,630 43,000 SH   OTR   43,000 0 0
GLAUKOS CORP COM 377322102   268,554 2,600 SH   OTR   2,600 0 0
GLOBUS MED INC CL A 379577208   12,394,200 210,000 SH   OTR   210,000 0 0
GRAIL INC COM 384747101   25,812,840 502,000 SH   OTR   502,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408   253,120 28,000 SH   OTR   28,000 0 0
GUARDANT HEALTH INC COM 40131M109   416,320 8,000 SH   OTR   8,000 0 0
HEALTHCARE RLTY TR CL A COM 42226K105   190,320 12,000 SH   OTR   12,000 0 0
HEALTHEQUITY INC COM 42226A107   33,502,248 319,800 SH   OTR   319,800 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   6,390,000 600,000 SH   OTR   600,000 0 0
HESS CORP COM 42809H107   804,224,700 5,805,000 SH   OTR   5,805,000 0 0
HIMS & HERS HEALTH INC COM CL A 433000106   409,447,013 8,213,581 SH   OTR   8,213,581 0 0
IMMUNOVANT INC COM 45258J102   192,000 12,000 SH   OTR   12,000 0 0
INSMED INC COM PAR $.01 457669307   301,920 3,000 SH   OTR   3,000 0 0
INTUIT COM 461202103   422,687,941 536,658 SH   OTR   536,658 0 0
INVESCO EXCHANGE TRADED FD T S&P500 EQL WGT 46137V357   418,002,000 2,300,000 SH Put OTR   2,300,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   44,720 26,000 SH   OTR   26,000 0 0
IQVIA HLDGS INC COM 46266C105   606,934,404 3,851,351 SH   OTR   3,851,351 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108   9,324 13,000 SH   OTR   13,000 0 0
ISHARES BITCOIN TRUST ETF SHS BEN INT 46438F101   429,697,261 7,020,050 SH   OTR   7,020,050 0 0
ISHARES TR IBOXX HI YD ETF 464288513   1,451,700,000 18,000,000 SH Put OTR   18,000,000 0 0
JANUX THERAPEUTICS INC COM 47103J105   1,108,800 48,000 SH   OTR   48,000 0 0
JD.COM INC NOTE 0.250% 6/0 47215PAJ5   41,822,000 40,000,000 PRN   OTR   40,000,000 0 0
JOYY INC ADS REPSTG COM A 46591M109   40,112,294 787,906 SH   OTR   787,906 0 0
KRYSTAL BIOTECH INC COM 501147102   274,920 2,000 SH   OTR   2,000 0 0
LANTHEUS HLDGS INC COM 516544103   550,281,502 6,722,227 SH   OTR   6,722,227 0 0
LATAM AIRLINES GROUP SA SPONSORED ADR 51817R205   12,927,259 318,092 SH   OTR   318,092 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   52,814,975 4,238,762 SH   OTR   4,238,762 0 0
LIVANOVA PLC SHS G5509L101   270,120 6,000 SH   OTR   6,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   1,004,462 3,319 SH   OTR   3,319 0 0
MARA HOLDINGS INC COM 565788106   13,092,800 835,000 SH   OTR   835,000 0 0
MASTERCARD INCORPORATED CL A 57636Q104   85,454,778 152,071 SH   OTR   152,071 0 0
MCKESSON CORP COM 58155Q103   230,532,588 314,600 SH   OTR   314,600 0 0
MERIT MED SYS INC COM 589889104   280,440 3,000 SH   OTR   3,000 0 0
MICROSOFT CORP COM 594918104   869,390,607 1,747,835 SH   OTR   1,747,835 0 0
MR COOPER GROUP INC COM 62482R107   18,278,225 122,500 SH   OTR   122,500 0 0
NASDAQ INC COM 631103108   365,168,299 4,083,743 SH   OTR   4,083,743 0 0
NATERA INC COM 632307104   814,596,412 4,821,809 SH   OTR   4,821,809 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581206   62,320,343 1,155,150 SH   OTR   1,155,150 0 0
NEW YORK TIMES CO CL A 650111107   314,022,385 5,609,546 SH   OTR   5,609,546 0 0
NOVAVAX INC COM NEW 670002401   100,800 16,000 SH   OTR   16,000 0 0
NUVALENT INC COM 670703107   11,445,000 150,000 SH   OTR   150,000 0 0
NVNI GROUP LIMITED *W EXP 11/01/202 G50716110   19,350 375,000 SH   OTR   375,000 0 0
OSCAR HEALTH INC CL A 687793109   31,645,440 1,476,000 SH   OTR   1,476,000 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   167,400 135,000 SH   OTR   135,000 0 0
PARAMOUNT GLOBAL CLASS B COM 92556H206   17,365,348 1,346,151 SH   OTR   1,346,151 0 0
PRIME MEDICINE INC COM 74168J101   1,852,500 750,000 SH   OTR   750,000 0 0
PROGYNY INC COM 74340E103   396,000 18,000 SH   OTR   18,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   341,126,772 6,172,006 SH   OTR   6,172,006 0 0
REVOLUTION MEDICINES INC *W EXP 12/17/202 76155X118   32,423 120,085 SH   OTR   120,085 0 0
REVOLUTION MEDICINES INC COM 76155X100   527,042,209 14,325,692 SH   OTR   14,325,692 0 0
ROIVANT SCIENCES LTD SHS G76279101   416,990 37,000 SH   OTR   37,000 0 0
SABRA HEALTH CARE REIT INC COM 78573L106   258,160 14,000 SH   OTR   14,000 0 0
SAGE THERAPEUTICS INC COM 78667J108   390,336 42,800 SH   OTR   42,800 0 0
SALESFORCE INC COM 79466L302   575,133,206 2,109,110 SH   OTR   2,109,110 0 0
SAVARA INC COM 805111101   15,583,800 6,835,000 SH   OTR   6,835,000 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   247,940 7,000 SH   OTR   7,000 0 0
SCHRODINGER INC COM 80810D103   22,252,720 1,106,000 SH   OTR   1,106,000 0 0
SCHWAB CHARLES CORP COM 808513105   361,224,361 3,959,057 SH   OTR   3,959,057 0 0
SOLENO THERAPEUTICS INC COM 834203309   418,900 5,000 SH   OTR   5,000 0 0
SOLID POWER INC *W EXP 12/08/202 83422N113   151,994 405,316 SH   OTR   405,316 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   3,398,175,000 5,500,000 SH   OTR   5,500,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   234,950 5,000 SH   OTR   5,000 0 0
SUMMIT MIDSTREAM CORPORATION COM 86614G101   1,427,989 58,214 SH   OTR   58,214 0 0
SURGERY PARTNERS INC COM 86881A100   42,814,980 1,926,000 SH   OTR   1,926,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   93,650 10,000 SH   OTR   10,000 0 0
TANGO THERAPEUTICS INC COM 87583X109   46,883,840 9,157,000 SH   OTR   9,157,000 0 0
TECTONIC THERAPEUTIC INC COM 878972108   16,950,104 853,050 SH   OTR   853,050 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   93,104,000 529,000 SH   OTR   529,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   560,848,896 1,383,241 SH   OTR   1,383,241 0 0
THIRD HARMONIC BIO INC COM 88427A107   83,410 15,361 SH   OTR   15,361 0 0
TRANSUNION COM 89400J107   475,602,600 5,404,575 SH   OTR   5,404,575 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   177,600 12,000 SH   OTR   12,000 0 0
TVARDI THERAPEUTICS INC COM 140755307   1,008,439 43,225 SH   OTR   43,225 0 0
TWIST BIOSCIENCE CORP COM 90184D100   281,444 7,650 SH   OTR   7,650 0 0
TYRA BIOSCIENCES INC COM 90240B106   10,946,338 1,143,818 SH   OTR   1,143,818 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   32,651,280 898,000 SH   OTR   898,000 0 0
UNIQURE NV SHS N90064101   195,160 14,000 SH   OTR   14,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   287,350 1,000 SH   OTR   1,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102   504,549,081 1,617,300 SH   OTR   1,617,300 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   171,189,800 1,810,000 SH   OTR   1,810,000 0 0
VERVE THERAPEUTICS INC COM 92539P101   40,562,760 3,612,000 SH   OTR   3,612,000 0 0
VISA INC COM CL A 92826C839   109,642,991 308,810 SH   OTR   308,810 0 0
VNET GROUP INC SPONSORED ADS A 90138A103   20,659,428 2,994,120 SH   OTR   2,994,120 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   2,223,650 715,000 SH   OTR   715,000 0 0
WABTEC COM 929740108   273,871,251 1,308,198 SH   OTR   1,308,198 0 0
WAYSTAR HLDG CORP COM 946784105   25,053,310 613,000 SH   OTR   613,000 0 0
WOODWARD INC COM 980745103   224,177,206 914,673 SH   OTR   914,673 0 0