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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
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SCHEDULE 13D/A 0001175707 XXXXXXXX LIVE 6 Common Stock, par value $0.001 per share (the "Shares") 05/16/2025 false 0000939767 30161Q104 EXELIXIS, INC. 1851 Harbor Bay Parkway Alameda CA 94502 Hannah E. Dunn (415) 421-2132 Farallon Capital Management, L.L.C. One Maritime Plaza, Suite 2100 San Francisco CA 94111 0001175707 Farallon Capital Partners, L.P. b WC CA 0 1537955 0 1537955 1537955 N 0.6 PN 0000886687 Farallon Capital Institutional Partners, L.P. b WC CA 0 1843011 0 1843011 1843011 N 0.7 PN 0001245628 Farallon Capital Institutional Partners II, L.P. b WC CA 0 516264 0 516264 516264 N 0.2 PN 0001245629 Farallon Capital Institutional Partners III, L.P. b WC DE 0 254155 0 254155 254155 N 0.1 PN 0001690212 Four Crossings Institutional Partners V, L.P. b WC DE 0 334531 0 334531 334531 N 0.1 PN 0001340990 Farallon Capital Offshore Investors II, L.P. b WC E9 0 3195280 0 3195280 3195280 N 1.2 PN 0001501082 Farallon Capital (AM) Investors, L.P. b WC DE 0 179796 0 179796 179796 N 0.1 PN 0001643763 Farallon Capital F5 Master I, L.P. b WC E9 0 644314 0 644314 644314 N 0.2 PN 0001871852 Farallon Healthcare Partners Master, L.P. b WC E9 0 10130194 0 10130194 10130194 N 3.7 PN 0001040153 Farallon Partners, L.L.C. b AF DE 0 17991186 0 17991186 17991186 N 6.6 OO Y Farallon Institutional (GP) V, L.L.C. b AF DE 0 334531 0 334531 334531 N 0.1 OO Y Farallon F5 (GP), L.L.C. b AF DE 0 644314 0 644314 644314 N 0.2 OO Y Farallon Healthcare Partners (GP), L.L.C. b AF DE 0 10130194 0 10130194 10130194 N 3.7 OO 0001960821 Dapice Joshua J. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001693981 Dreyfuss, Philip D. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001960890 Dunn Hannah E. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001245637 Fried, Richard B b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001904298 Gehani, Varun N. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001372970 Giauque, Nicolas b AF I0 0 18635500 0 18635500 18635500 N 6.8 IN 0001595643 Kim, David T. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001495856 Linn, Michael G. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0002054041 Luo Patrick (Cheng) b AF F4 0 18635500 0 18635500 18635500 N 6.8 IN 0001275110 Patel, Rajiv A. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001453042 Roberts, Jr., Thomas G. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001960819 Saito Edric C. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001693980 Seybold, William b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001960871 Short Daniel S. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001372968 Spokes, Andrew J. M. b AF X0 0 18635500 0 18635500 18635500 N 6.8 IN 0001509711 Warren, John R. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN 0001245635 Wehrly, Mark C. b AF X1 0 18635500 0 18635500 18635500 N 6.8 IN Common Stock, par value $0.001 per share (the "Shares") EXELIXIS, INC. 1851 Harbor Bay Parkway Alameda CA 94502 This Amendment No. 6 to Schedule 13D (this "Amendment") hereby amends and supplements Item 5(a) by deleting the text under the caption "The Farallon Funds" and replacing it in its entirety, to read as follows: "The information set forth in Rows 7 through 13 of the cover page hereto for each Farallon Fund is incorporated herein by reference for each such Farallon Fund. The percentage amount set forth in Row 13 for all cover pages filed herewith is calculated based upon the 272,708,280 Shares outstanding as of May 5, 2025, as reported by the Company in its Form 10-Q filed with the Securities and Exchange Commission on May 13, 2025." This Amendment hereby amends and supplements Item 5(b) by deleting the text under the caption "The Farallon Funds" and replacing it in its entirety, to read as follows: "The information set forth in Rows 7 through 13 of the cover page hereto for each Farallon Fund is incorporated herein by reference for each such Farallon Fund." This Amendment hereby amends and supplements Item 5(c) by deleting the text under the caption "The Farallon Funds" and replacing it in its entirety, to read as follows: "The dates, number of Shares involved and the price per Share (excluding commissions) for all transactions in the Shares by the Farallon Funds in the past sixty days are set forth in Exhibit 1.A attached hereto and such information is incorporated herein by reference. All of such transactions were open-market transactions." This Amendment hereby amends and supplements Item 5(d) by deleting the text under the caption "The Farallon Funds" and replacing it in its entirety, to read as follows: "The Farallon General Partner has the power to direct the receipt of dividends relating to, or the disposition of the proceeds of the sale of, the Shares held by the Farallon Funds other than F5MI. The FCIP V General Partner has the power to direct the receipt of dividends relating to, or the disposition of the proceeds of the sale of, the Shares held by FCIP V. The F5MI General Partner has the power to direct the receipt of dividends relating to, or the disposition of the proceeds of the sale of, the Shares held by F5MI. The FHPM General Partner has the power to direct the receipt of dividends relating to, or the disposition of the proceeds of the sale of, the Shares held by FHPM. Each of the Farallon Individual Reporting Persons is a managing member or senior managing member, as the case may be, of the Farallon General Partner and a manager or senior manager, as the case may be, of the FCIP V General Partner, the F5MI General Partner and the FHPM General Partner." This Amendment hereby amends and supplements Item 5(e) by deleting the text under the caption "The Farallon Funds" and replacing it in its entirety, to read as follows: "Not applicable." This Amendment hereby amends and supplements Item 7 by adding the following thereto: "There is filed herewith as Exhibit 1.A the sixty-day trading history of the Farallon Funds referenced in Item 5(c)." Farallon Capital Partners, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital Institutional Partners, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital Institutional Partners II, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital Institutional Partners III, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Four Crossings Institutional Partners V, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital Offshore Investors II, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital (AM) Investors, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Capital F5 Master I, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Healthcare Partners Master, L.P. /s/ Hannah E. Dunn Hannah E. Dunn, Manager of its General Partner 05/20/2025 Farallon Partners, L.L.C. /s/ Hannah E. Dunn Hannah E. Dunn, Managing Member 05/20/2025 Farallon Institutional (GP) V, L.L.C. /s/ Hannah E. Dunn Hannah E. Dunn, Manager 05/20/2025 Farallon F5 (GP), L.L.C. /s/ Hannah E. Dunn Hannah E. Dunn, Manager 05/20/2025 Farallon Healthcare Partners (GP), L.L.C. /s/ Hannah E. Dunn Hannah E. Dunn, Manager 05/20/2025 Dapice Joshua J. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Dreyfuss, Philip D. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Dunn Hannah E. /s/ Hannah E. Dunn Hannah E. Dunn 05/20/2025 Fried, Richard B /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Gehani, Varun N. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Giauque, Nicolas /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Kim, David T. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Linn, Michael G. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Luo Patrick (Cheng) /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Patel, Rajiv A. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Roberts, Jr., Thomas G. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Saito Edric C. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Seybold, William /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Short Daniel S. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Spokes, Andrew J. M. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Warren, John R. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025 Wehrly, Mark C. /s/ Hannah E. Dunn Hannah E. Dunn, as attorney-in-fact 05/20/2025