Exhibit 31.4
CERTIFICATION
I, Marsha H. Fanucci, certify that:
1. I have reviewed this Amendment No. 1 on Form 10-Q/A of Millennium Pharmaceuticals, Inc.; and
2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.
| Date: November 9, 2006 | 
 | /s/ MARSHA H. FANUCCI | 
| 
 | 
 | Marsha H. Fanucci | 
| 
 | 
 | Senior Vice President and Chief Financial Officer |