February 11, 2019 Dan Peisert Senior Vice President and Chief Financial Officer Assertio Therapeutics, Inc 100 South Saunders Road, Suite 300 Lake Forest, IL 60045 Re: Assertio Therapeutics, Inc Form 10-K for the fiscal year ended December 31, 2017 Filed March 1, 2018 File No. 001-13111 Dear Mr. Peisert: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance