Filed Pursuant to Rule 424(b)(3)

Registration No. 333-182326

PROSPECTUS SUPPLEMENT NO. 11

(To Prospectus Dated July 20, 2012,

Prospectus Supplement No. 1 dated August 3, 2012,

Prospectus Supplement No. 2 dated August 14, 2012,

Prospectus Supplement No. 3 dated November 21, 2012,

Prospectus Supplement No. 4 dated December 14, 2012,

Prospectus Supplement No. 5 dated December 20, 2012,

Prospectus Supplement No. 6 dated January 11, 2013,

Prospectus Supplement No. 7 dated February 1, 2013,

Prospectus Supplement No. 8 dated February 28, 2013,

Prospectus Supplement No. 9 dated April 4, 2013 and

Prospectus Supplement No. 10 dated April 5, 2013)

GRANDPARENTS.COM, INC.

19,775,632 SHARES OF COMMON STOCK

This Prospectus Supplement No. 11 (this “Supplement”) supplements the Prospectus dated July 20, 2012, Prospectus Supplement No. 1 dated August 3, 2012, Prospectus Supplement No. 2 dated August 14, 2012, Prospectus Supplement No. 3 dated November 21, 2012, Prospectus Supplement No. 4 dated December 14, 2012, Prospectus Supplement No. 5 dated December 20, 2012, Prospectus Supplement No. 6 dated January 11, 2013, Prospectus Supplement No. 7 dated February 1, 2013, Prospectus Supplement No. 8 dated February 28, 2013, Prospectus Supplement No. 9 dated April 4, 2013 and Prospectus Supplement No. 10 dated April 5, 2013 (collectively, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-182326). This Supplement and the Prospectus relate to the resale by the selling security holders identified in the Prospectus (the “Selling Security Holders”) of up to 19,775,632 shares of common stock, par value $.01 per share (“Common Stock”), of Grandparents.com, Inc. (the “Company”) including (i) up to 12,897,172 shares of Common Stock (the “Investor Shares”) issued upon conversion of the Company’s Series B Convertible Preferred Stock, par value $.01 per share, issued pursuant to the Company’s private placement completed on February 23, 2012, (ii) up to 5,588,749 shares of Common Stock (the “Advisory Warrant Shares”) issuable upon the exercise of warrants (the “Advisory Warrants”) issued to the Company’s investment banking advisor as partial compensation for its services in connection with the asset contribution transaction completed on February 23, 2012 and to the investment banking advisor’s assignees, and (iii) up to 1,289,711 shares of Common Stock (the “Placement Agent Warrant Shares” and together with the Advisory Warrant Shares, the “Warrant Shares”) issuable upon the exercise of warrants (the “Placement Agent Warrants” and, together with the Advisory Warrants, the “Warrants”) issued to the Company’s placement agent as partial compensation for its services in connection with the Company’s private placement completed on February 23, 2012 and to the placement agent’s assignees. The Investor Shares and the Warrant Shares (collectively, the “Shares”) are being offered by the Selling Security Holders.

The Company is not selling any of the Shares and, as a result, it will not receive any proceeds from the sale of the Shares covered by the Prospectus and this Supplement other than proceeds in the event that some or all of the Warrants held by the Selling Security Holders are exercised for cash. All of the net proceeds from the sale of the Shares will go to the Selling Security Holders.

This Supplement contains the Current Report on Form 8-K dated April 4, 2013 filed by the Company with the Securities and Exchange Commission on April 9, 2013 and updates, amends and supplements the information included or incorporated by reference in the Prospectus. This Supplement should be read in conjunction with the Prospectus, which is to be delivered with this Supplement. If there is any inconsistency between the information in this Supplement and the Prospectus, you should rely on the information in this Supplement. This Supplement is not complete without, and may not be delivered or utilized except in connection with, the Prospectus, including any amendments or supplements to it.

Investing in the Shares involves a high degree of risk. You should carefully consider the risk factors beginning on page 3 of the Prospectus before purchasing any Shares.

NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS SUPPLEMENT OR THE PROSPECTUS IS TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.

The date of this Supplement is April 10, 2013

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the

Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): April 4, 2013

Grandparents.com, Inc.

(Exact name of registrant as specified in its charter)

Registrant’s telephone number, including area code: 646-839-8800

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

On April 4, 2013, and effective as of April 2, 2013, the Company entered into a Second Amended and Restated Promissory Note in favor of Mel Harris (the “Second Amended and Restated Harris Note”), which amends and restates the amended and restated promissory note issued by the Company to Mr. Harris in January 2013 (the “First Amended and Restated Harris Note”) in connection with a loan by Mr. Harris to the Company in the original principal amount of $200,000 (the “Loan”). The Second Amended and Restated Harris Note extends the maturity date of the Loan to July 1, 2013. The other material terms and conditions of the Second Amended and Restated Harris Note are substantially the same as the First Amended and Restated Harris Note.

The description of the terms of the Second Amended and Restated Harris Note does not purport to be complete and such description is qualified in its entirety by reference to the copy of the Second Amended and Restated Harris Note to be filed as an exhibit to the Company’s Annual Report on Form 10-K for the year ended December 31, 2012 and incorporated herein by reference.

On April 2, 2013, the Company issued a five-year warrant to purchase 500,000 shares of its common stock at an exercise price of $0.25 per share. The exercise price and number of shares for which the warrant is exercisable are subject to adjustments for certain customary events. The warrant was issued in exchange for services performed for the Company by the recipient. The warrant may be exercised on a cashless basis.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.