UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 14A
Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934
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Pernix Therapeutics Holdings, Inc.
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YOUR IMMEDIATE ACTION IS REQUESTED
Please Vote Your Shares for the May 22nd Annual Meeting Today
JOHN A. SEDOR
Chairman and
Chief Executive Officer
April 30, 2018
Dear Pernix Therapeutics Holdings, Inc. Stockholder:
We recently mailed to you proxy materials for our 2018 Annual Meeting of Stockholders to be held at the Hyatt Morristown at Headquarters Plaza, 3 Speedwell Avenue, Morristown, New Jersey 07960, on May 22, 2018 at 9:30 a.m., local time. Your vote is extremely important regardless of the number of shares you own.
At the Annual Meeting, you are being asked to vote on six proposals. Our Board of Directors (the "Board") unanimously recommended that you vote FOR each of the five Board nominees and FOR each of the proposals.
I would like to take this opportunity to highlight Proposals 2, 3, 4 and 5 specifically and discuss why each are in the best interests of our stockholders.
Proposal 2 asks our stockholders to approve an amendment to increase the number of shares reserved under the 2017 Omnibus Incentive Plan (the "Incentive Plan") by 600,000 shares of our common stock. We believe this proposal is in the best interests of our stockholders for the following reasons:
Proposal 3 asks our stockholders to approve an amendment to our charter to provide for a "majority voting standard" with respect to stockholder approval of business combinations and certain other extraordinary corporate actions. This proposal benefits our stockholders in the following ways:
10 North Park Place, Suite 201 | Morristown, NJ 07960 | 800.793.2145 | www.pernixtx.com
This proposal requires approval from a majority of our outstanding shares, so not voting is the same as a vote against.
Proposal 4: On February 28, 2018, the Board adopted an amendment to the Company's bylaws for an "exclusive forum selection" provision (the "Exclusive Forum Amendment"), meaning that the exclusive forum for specified legal actions involving Pernix generally will be in the Circuit Court of Baltimore City, Maryland (or, in certain circumstances, the United States District Court for the District of Maryland in Baltimore). While stockholder approval is not required to approve this amendment, the Board has nevertheless decided to request that our stockholders ratify this Exclusive Forum Amendment on an advisory basis. The expected benefits are:
Proposal 5 seeks stockholder approval of the compensation practices related to our named executive officers. This vote is not intended to address the specific compensation arrangement of any officer, but rather the overall compensation practices related to our senior executive officers, as disclosed in our proxy statement.
This non-binding advisory proposal, commonly known as a "say-on-pay" proposal, is required under Section 14A of the Securities Exchange Act of 1934, as amended by the Dodd-Frank Wall Street Reform and Consumer Protection Act, which was enacted in July 2010.
The Company's compensation policies are intended to align the executives' incentives with the achievement of Pernix's strategic goals, which should ultimately also enhance stockholder value by:
The Board, with the advice of its independent compensation expert, has attempted to put in place executive compensation structures that properly incentivize our executives to achieve the Company's strategic goals. The Company's independent compensation expert makes recommendations to the Company's Board that focus upon three primary components: base salary, annual cash incentives and long-term equity awards. The Board, using this information, then creates linkage to pre-established pay-for performance metrics, balancing both the short and long-term goals and objectives of the Company.
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How to Vote
Your vote is important. Whether you own relatively few or a large number of shares of our stock, it is important that your shares be represented and voted at the 2018 Annual Meeting.
With the May 22nd Annual Meeting only a short time away, we encourage you to vote online, by telephone or by mail in the enclosed pre-paid return envelope.
Thank you for voting.

John A. Sedor
Chairman and Chief Executive Officer
If you have any questions, please call the firm assisting us with the solicitation of proxies,
Saratoga Proxy Consulting LLC, at (212) 257-1311 or (888) 368-0379.
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