United States securities and exchange commission logo May 3, 2021 Neil Sorahan Chief Financial Officer Ryanair Holdings plc c/o Ryanair DAC Dublin Office Airside Business Park, Swords County Dublin, K67 NY94, Ireland Re: Ryanair Holdings plc Form 20-F for Fiscal Year Ended March 31, 2020 July 28, 2020 Form 6-K Filed on February 1, 2021 000-29304 Dear Mr. Sorahan: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Energy & Transportation cc: David I. Gottlieb