EXHIBIT 15.1

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Consent of Independent Registered Public Accounting Firm

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We consent to the incorporation by reference in the registration statements No. 333-268265, No. 333-261182, No. 333-259857, No. 333-257142 and No. 333-217160 on Form S-8 and No. 333-255101 on Form F-3 of our reports dated April 7, 2023, with respect to the consolidated financial statements of EDAP TMS S.A. and subsidiaries, and the effectiveness of internal control over financial reporting.

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Lyon, April 7, 2023

KPMG S.A.

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Sara Claire Righenzi Hugon de Villers

Partner