United States securities and exchange commission logo August 27, 2021 Thomas Freeburg Chief Financial Officer Interpace Biosciences, Inc. Morris Corporate Center 1, Building C 300 Interpace Parkway Parsippany, NJ 07054 Re: Interpace Biosciences, Inc. Form 10-K for the Fiscal Year Ended December 31, 2020 Filed April 1, 2021 File No. 000-24249 Dear Mr. Freeburg: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences