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EXHIBIT 22.1

List of Issuers of Debt Securities Guaranteed by Enterprise Products Partners L.P. and Associated Securities at June 30, 2025.

In compliance with Item 601(b)(22) of Regulation S-K, the following is a list of publicly traded debt securities issued by Enterprise Products Operating LLC (the “Subsidiary Issuer”) and guaranteed by Enterprise Products Partners L.P. (the “Parent Guarantor”) (dollars in millions):

			Amounts Outstanding at
Guaranteed Securities			June 30, 2025
Senior Notes FFF, 5.05% fixed-rate, due January 2026			$	750
Senior Notes PP, 3.70% fixed-rate, due February 2026			875
Senior Notes HHH, 4.60% fixed-rate, due January 2027			1,000
Senior Notes SS, 3.95% fixed-rate, due February 2027			575
Senior Notes LLL, 4.30%, fixed-rate, due June 2028			500
Senior Notes WW, 4.15% fixed-rate, due October 2028			1,000
Senior Notes YY, 3.125% fixed-rate, due July 2029			1,250
Senior Notes AAA, 2.80% fixed-rate, due January 2030			1,250
Senior Notes MMM, 4.60% fixed-rate, due January 2031			750
Senior Notes GGG, 5.35% fixed-rate, due January 2033			1,000
Senior Notes D, 6.875% fixed-rate, due March 2033			500
Senior Notes III, 4.85% fixed-rate, due January 2034			1,000
Senior Notes H, 6.65% fixed-rate, due October 2034			350
Senior Notes JJJ, 4.95% fixed-rate, due February 2035			1,100
Senior Notes J, 5.75% fixed-rate, due March 2035			250
Senior Notes NNN, 5.20% fixed-rate, due January 2036			750
Senior Notes W, 7.55% fixed-rate, due April 2038			400
Senior Notes R, 6.125% fixed-rate, due October 2039			600
Senior Notes Z, 6.45% fixed-rate, due September 2040			600
Senior Notes BB, 5.95% fixed-rate, due February 2041			750
Senior Notes DD, 5.70% fixed-rate, due February 2042			600
Senior Notes EE, 4.85% fixed-rate, due August 2042			750
Senior Notes GG, 4.45% fixed-rate, due February 2043			1,100
Senior Notes II, 4.85% fixed-rate, due March 2044			1,400
Senior Notes KK, 5.10% fixed-rate, due February 2045			1,150
Senior Notes QQ, 4.90% fixed-rate, due May 2046			975
Senior Notes UU, 4.25% fixed-rate, due February 2048			1,250
Senior Notes XX, 4.80% fixed-rate, due February 2049			1,250
Senior Notes ZZ, 4.20% fixed-rate, due January 2050			1,250
Senior Notes BBB, 3.70% fixed-rate, due January 2051			1,000
Senior Notes DDD, 3.20% fixed-rate, due February 2052			1,000
Senior Notes EEE, 3.30% fixed-rate, due February 2053			1,000
Senior Notes NN, 4.95% fixed-rate, due October 2054			400
Senior Notes KKK, 5.55% fixed-rate, due February 2055			1,400
Senior Notes CCC, 3.95% fixed-rate, due January 2060			1,000
Junior Subordinated Notes C, variable-rate, due June 2067			232
Junior Subordinated Notes D, variable-rate, due August 2077			350
Junior Subordinated Notes E, fixed/variable-rate, due August 2077			1,000
Junior Subordinated Notes F, fixed/variable-rate, due February 2078			700