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Exhibit 29

SEVENTH AMENDED AND RESTATED JOINT FILING AGREEMENT

This Seventh Amended and Restated Joint Filing Agreement (this “Agreement”) amends and restates the Sixth Amended and Restated Joint Filing Agreement, dated July 29, 2024.

Pursuant to and in accordance with the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder (the “Exchange Act”) the undersigned hereby agree to the joint filing on behalf of each of them of any filing required by such party under Section 13 of the Exchange Act or any rule or regulation thereunder (including any amendment, restatement, supplement, and/or exhibit thereto) with respect to securities of Lexicon Pharmaceuticals, Inc., a Delaware corporation, and further agree to the filing, furnishing, and/or incorporation by reference of this Agreement as an exhibit thereto. Each of them is responsible for the timely filing of each such filings and any amendments thereto, and for the completeness and accuracy of the information concerning such person contained therein; but none of them is responsible for the completeness or accuracy of the information concerning the other persons making the filing, unless such person knows or has reason to believe that such information is inaccurate. This Agreement shall remain in full force and effect until revoked by any party hereto in a signed writing provided to each other party hereto, and then only with respect to such revoking party. This Agreement may be executed in any number of counterparts all of which taken together shall constitute one and the same instrument.

Dated: December 9, 2024

 

INVUS, L.P.
By: INVUS ADVISORS, L.L.C., its general partner
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
INVUS PUBLIC EQUITIES, L.P.
By: INVUS PUBLIC EQUITIES ADVISORS, LLC, its general partner
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
INVUS ADVISORS, L.L.C.
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
INVUS PUBLIC EQUITIES ADVISORS, LLC
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President


INVUS GLOBAL MANAGEMENT, LLC
By:  

/s/ Raymond Debbane

Name: Raymond Debbane
Title: President
SIREN, L.L.C.
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
ARTAL PARTICIPATIONS S.À R.L.
By:  

/s/ Pierre Claudel

Name:   Pierre Claudel
Title:   Manager
ARTAL INTERNATIONAL S.C.A.
By: Artal International Management S.A., its managing partner
By:  

/s/ Pierre Claudel

Name:   Pierre Claudel
Title:   Managing Director
ARTAL INTERNATIONAL MANAGEMENT S.A.
By:  

/s/ Pierre Claudel

Name:   Pierre Claudel
Title:   Managing Director
ARTAL GROUP S.A.
By:  

/s/ Anne Goffard

Name:   Anne Goffard
Title:   Authorized Person
WESTEND S.A.
By:  

/s/ Pierre Claudel

Name:   Pierre Claudel
Title:   Managing Director
STICHTING ADMINISTRATIEKANTOOR WESTEND
By:  

/s/ Amaury Wittouck

Name:   Amaury Wittouck
Title:   Sole Member of the Board
AMAURY WITTOUCK
By:  

/s/ Amaury Wittouck


INVUS US PARTNERS LLC
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
ULYS, L.L.C.
By:  

/s/ Raymond Debbane

Name:   Raymond Debbane
Title:   President
RAYMOND DEBBANE
By:  

/s/ Raymond Debbane