Exhibit 32.1
CERTIFICATION OF THE EXECUTIVE CHAIRMAN OF THE BOARD OF DIRECTORS AND CHIEF FINANCIAL OFFICER PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
(18 U.S.C. Section 1350)
Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, each of the undersigned officers of Cassava Sciences, Inc. (the “Company”), hereby certifies that to the best of such officer’s knowledge:
| 1. | The Company’s Quarterly Report on Form 10-Q for the period ended September 30, 2024, and to which this certification is attached as Exhibit 32.1 (the “Periodic Report”), fully complies with the requirements of Section 13-(a) or 15-(d) of the Securities Exchange Act of 1934, and | 
| 2. | The information contained in the Periodic Report fairly presents, in all material respects, the financial condition and results of operations of the Company. | 
Date: November 7, 2024
|  | /s/ RICHARD J. BARRY | |
|  | Richard J. Barry | |
|  | President and Chief Executive Officer | |
| (Principal Executive Officer) | ||
|  | /s/ ERIC J. SCHOEN | |
|  | Eric J. Schoen, | |
|  | Chief Financial Officer | |
| (Principal Financial and Accounting Officer) | ||