EXHIBIT 23.1

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Consent of Independent Registered Public Accounting Firm

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We consent to the incorporation by reference in the registration statements on Form S-8 (No. 333-197236 and No. 333-212445) and Form F-3 (No. 333-213649 and No. 333-258949) of our report dated April 17, 2023, with respect to the consolidated financial statements of Materialise NV and the effectiveness of internal control over financial reporting.

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KPMG Bedrijfsrevisoren BV / KPMG Réviseurs d’Entreprises SRL

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/s/ Gotwin Victor Jaak Jackers

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Zaventem, Belgium

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April 17, 2023