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As filed with the Securities and Exchange Commission on December 20, 2005
Registration No. 333-127893

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549


POST-EFFECTIVE AMENDMENT NO. 1
FORM SB-2
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933


FIRST NATIONAL BANCSHARES, INC.
(Exact name of registrant as specified in its charter)



    South Carolina   6021   58-2466370  
    (state or other jurisdiction   (Primary Standard Industrial   (I.R.S. Employer 
    of incorporation or   Classification Code Number)   Identification No.) 
    organization) 

215 North Pine Street
Spartanburg, South Carolina 29302
(864) 948-9001
     (Address and Telephone Number of Intended Place of Business)


Jerry L. Calvert
President and Chief Executive Officer
215 North Pine Street
Spartanburg, South Carolina 29302
(864) 948-9001
(Name, Address and Telephone Number of Agent for Service)


Copies of all communications, including copies of all communications
sent to agent for service, should be sent to:

Neil E. Grayson, Esq.
Hamilton E. Russell, III, Esq.
Nelson Mullins Riley & Scarborough LLP
Poinsett Plaza, Suite 900
104 South Main Street
Greenville, South Carolina 29601
Telephone: (864) 250-2235
Fax: (864) 232-2359


        If any of the securities being registered on this form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box. [  ]

        An aggregate of 833,500 shares of common stock (including 86,000 shares of a selling shareholder) were initially registered in the offering that was declared effective by the Securities and Exchange Commission on October 14, 2005.

        The Registrant’s offering was terminated on December 2, 2005. A total of 369,282 shares were sold in the offering, including 283,282 shares of common stock issued by the Registrant and 86,000 shares sold by the selling shareholder. The remaining 464,218 shares of common stock registered in the offering are hereby deregistered.


SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the registrant has duly caused this Post-Effective Amendment No. 1 to the Registration Statement on Form SB-2 to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Spartanburg, State of South Carolina, on December 20, 2005.

FIRST NATIONAL BANCSHARES, INC.


By:   /s/ Jerry L. Calvert        
        Jerry L. Calvert
        President and Chief Executive Officer

Pursuant to the requirements of the Securities Act of 1933, this Post-Effective Amendment No. 1 to the Registration Statement has been signed by the following in the capacities and on the dates indicated.

Signature Title Date

/s/ C. DAN ADAMS*
C. Dan Adams
Director December 20, 2005


/s/ MELLNEE G. BUCHHEIT*
Mellnee G. Buchheit
Director December 20, 2005



/s/ JERRY L. CALVERT
Jerry L. Calvert
President, Chief Executive
Officer, and Vice Chairman
December 20, 2005



/s/ MARTHA C. CHAPMAN*
Martha C. Chapman
Director December 20, 2005



/s/ W. RUSSEL FLOYD, JR.*
W. Russel Floyd, Jr.
Director December 20, 2005



/s/ C. TYRONE GILMORE, SR.*
C. Tyrone Gilmore, Sr.
Director December 20, 2005



/s/ DR. GAINES W. HAMMOND, JR.*
Dr. Gaines W. Hammond, Jr.
Chairman of the Board December 20, 2005



20


/s/ BENJAMIN R. HINES*
Benjamin R. Hines
Director December 20, 2005



/s/ WILLIAM A. HUDSON*
William A. Hudson
Director December 20, 2005



/s/ KITTY B. PAYNE*
Kitty B. Payne
Executive Vice President and
Chief Financial Officer
December 20, 2005



/s/ NORMAN F. PULLIAM*
Norman F. Pulliam
Director, Chairman
Emeritus of the Board
December 20, 2005



/s/ PETER E. WEISMAN*
Peter E. Weisman
Director December 20, 2005



/s/ DONALD B. WILDMAN*
Donald B. Wildman
Director December 20, 2005



/s/ COLEMAN L. YOUNG, JR.*
Coleman L. Young, Jr.
Director December 20, 2005



*By: /s/ JERRY L. CALVERT
Jerry L. Calvert, as Attorney-in-Fact
December 20, 2005