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Exhibit 21.1

The following is a list of subsidiaries of Edwards Lifesciences Corporation, omitting subsidiaries which, considered in the aggregate as a single subsidiary, would not constitute a significant subsidiary as of December 31, 2023:

Legal Entity

State of Incorporation/ Formation

Country of Incorporation/ Formation

Edwards Lifesciences LLC

Delaware

U.S.

Edwards Lifesciences Services GmbH

Germany

Edwards Lifesciences (U.S.) Inc.

Delaware

U.S.

Edwards Lifesciences (Japan) Limited

Japan