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May 15, 2025

VIA EDGAR SUBMISSION

Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, NE

Washington, DC 20549

Attention:			Tyler Howes
Re:			Curis, Inc.
			Registration Statement on Form S-3
			File No. 333-287014
			Request for Acceleration

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Curis, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-287014), so that it may become effective at 4:30 p.m., Eastern Time, on May 19, 2025, or as soon as practicable thereafter.

Very truly yours,

CURIS, INC.

By: /s/ Diantha Duvall        

Name: Diantha Duvall

Title: Chief Financial Officer

128 Spring Street | Building C – Suite 500 | Lexington, MA 02421-3112 | www.curis.com | Phone 617.503.6500