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Exhibit 23.3

CONSENT OF INDEPENDENT AUDITORS

We consent to the incorporation by reference in this Registration Statement on Form S-3 of OraSure Technologies, Inc. of our report dated March 5, 2025, relating to the consolidated financial statements of Sherlock Biosciences, Inc., appearing in the Current Report on Form 8-K/A filed by OraSure Technologies, Inc. on March 7, 2025. We also consent to the reference of our firm under the heading “Experts” in such

Registration Statement.

/s/ Baker Newman & Noyes LLC

Boston, Massachusetts

May 20, 2025