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Exhibit 23.1

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Consent of Independent Registered Public Accounting Firm

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We consent to the reference to our firm under the caption “Experts” and to the use of our report dated March 7, 2024, in the Registration Statement (Form S-1) and related Prospectus of Bio-Path Holdings, Inc. dated January 17, 2025.

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/s/ Ernst & Young LLP

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Houston, Texas

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January 17, 2025

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