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    <filerInfo>
      <liveTestFlag>LIVE</liveTestFlag>
      <filer>
        <issuerCredentials>
          <cik>0001133818</cik>
          <ccc>XXXXXXXX</ccc>
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      <flags>
        <successorFilingFlag>N</successorFilingFlag>
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    <item1>
      <issuerName>Bio-Path Holdings, Inc.</issuerName>
      <street1>625 Stanwix Street</street1>
      <street2>#2407</street2>
      <city>Pittsburgh</city>
      <stateOrCountry>PA</stateOrCountry>
      <zipCode>15222</zipCode>
      <phone>630-708-0750</phone>
      <commissionFileNumber>024-12601</commissionFileNumber>
    </item1>
    <summaryInfoOffering>
      <offeringQualificationDate>05-29-2025</offeringQualificationDate>
      <offeringCommenceDate>05-30-2025</offeringCommenceDate>
      <offeringSecuritiesQualifiedSold>35714285</offeringSecuritiesQualifiedSold>
      <offeringSecuritiesSold>0</offeringSecuritiesSold>
      <pricePerSecurity>0.1400</pricePerSecurity>
      <portionSecuritiesSoldIssuer>0.00</portionSecuritiesSoldIssuer>
      <portionSecuritiesSoldSecurityholders>0.00</portionSecuritiesSoldSecurityholders>
      <underwrittenSpName>D. Boral Capital</underwrittenSpName>
      <underwriterFees>0.00</underwriterFees>
      <salesCommissionsSpName>n/a</salesCommissionsSpName>
      <salesCommissionsFee>0.00</salesCommissionsFee>
      <findersSpName>n/a</findersSpName>
      <findersFees>0.00</findersFees>
      <auditorSpName>Ernst &amp; Young</auditorSpName>
      <auditorFees>0.00</auditorFees>
      <legalSpName>Winstead PC</legalSpName>
      <legalFees>0.00</legalFees>
      <promoterSpName>n/a</promoterSpName>
      <promotersFees>0.00</promotersFees>
      <blueSkySpName>n/a</blueSkySpName>
      <blueSkyFees>0.00</blueSkyFees>
      <issuerNetProceeds>0.00</issuerNetProceeds>
      <clarificationResponses>No securities were sold in the Offering. Amount of securities qualified in the Offering is based on the post qualification Offering Circular supplement filed on June 2, 2025 under 253(g)(3).</clarificationResponses>
    </summaryInfoOffering>
    <certificationSuspension>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <certificationFileNumber>024-12601</certificationFileNumber>
      <approxRecordHolders>462</approxRecordHolders>
    </certificationSuspension>
    <signatureTab>
      <cik>0001133818</cik>
      <regulationIssuerName1>BIO-PATH HOLDINGS, INC.</regulationIssuerName1>
      <regulationIssuerName2>BIO-PATH HOLDINGS, INC.</regulationIssuerName2>
      <signatureBy>Vikram Grover</signatureBy>
      <date>02-25-2026</date>
      <title>CEO</title>
    </signatureTab>
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