United States securities and exchange commission logo August 16, 2021 Chaim Lebovits Chief Executive Officer BRAINSTORM CELL THERAPEUTICS INC. 1325 Avenue of Americas, 28th Floor New York, NY 10019 Re: BRAINSTORM CELL THERAPEUTICS INC. Registration Statement on Form S-3 Filed August 9, 2021 File No. 333-258640 Dear Mr. Lebovits: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Laura Crotty at 202-551-7614 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Jesse Nevarez