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Exhibit 107

Calculation of Filing Fee Tables

424(b)(5)

(Form Type)

Madrigal Pharmaceuticals, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

 

     Security
  Type
 

Security

Class Title

 

Fee

Calculation

or Carry
Forward

Rule

 

Amount

Registered

 

Proposed

Maximum

Offering

Price

Per Unit

 

Maximum

Aggregate

Offering

Price

   

Fee

Rate

   

Amount of

Registration

Fee (1)

 
Newly Registered Securities

 

Fees to Be

Paid

  Equity    Common Stock,

$0.0001

par value per share

  Rule 457(r)   2,653,845(2)   $260.00   $ 689,999,700       0.00014760     $ 101,844  

Fees to Be

Paid

  Equity    Pre-funded warrants

to purchase

common stock

  Rule 457(r)   2,653,845   $260.00(3)     (3)       0.00014760       (3)  

Fees Previously Paid

  N/A   N/A   N/A   N/A   N/A     N/A               N/A  
Carry Forward Securities

 

Carry Forward Securities

  N/A   N/A   N/A   N/A         N/A                  
    Total Offering Amounts        $ 689,999,700             $ 101,844  
    Total Fees Previously Paid                           
    Total Fee Offsets                           
    Net Fee Due                        $ 101,844  

 

(1)

Calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended (the “Securities Act”). In accordance with Rules 456(b) and 457(r) under the Securities Act the registrant initially deferred payment of all of the registration fees for the Registration Statement on Form S-3 (Registration No. 333-256666), filed on June 1, 2021.

(2)

Includes 346,153 shares of common stock that the underwriters have an option to purchase and 1,557,692 shares of common stock that are issuable upon exercise of the pre-funded warrants referenced below.

(3)

Represents the sum of the pre-funded warrants sales price of $259.9999 per pre-funded warrant and the exercise price of $0.0001 per share issuable pursuant to the pre-funded warrants. Pursuant to Securities and Exchange Commission staff interpretation, the entire fee is allocated to the common stock underlying the pre-funded warrants.