Exhibit 1.01

Glaukos Corporation

Conflict Minerals Report

for the Year Ended December 31, 2025

Glaukos Corporation (“Glaukos,” “the Company,” “we,” “our,” and “us”) has filed this Conflict Minerals Report (“CMR”) for the year ended December 31, 2025 to comply with Rule 13p-1 under the Securities Exchange Act of 1934 (the “Rule”). The Rule imposes certain reporting obligations on U.S. Securities and Exchange Commission (“SEC”) issuers whose manufactured products contain certain minerals which are necessary to the functionality or production of their products. These minerals are cassiterite, columbite-tantalite (coltan), gold, wolframite, and their derivatives, which are limited to tin, tantalum and tungsten (“3TG” or “Conflict Minerals”). The Rule focuses on 3TG emanating from the Democratic Republic of Congo (“DRC”) region and nine adjoining countries (together, the “Covered Countries”). If any Conflict Minerals contained in an issuer’s manufactured products that are necessary to the functionality or production of such products may have originated in the Covered Countries, or if the issuer is unable to determine the country of origin of those Conflict Minerals, then the issuer must exercise due diligence on the Conflict Minerals’ source and chain of custody and submit a CMR to the SEC that includes a description of those due diligence measures.

Forward-Looking Statements and Other Disclaimers

This Specialized Disclosure Report on Form SD contains forward looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. These statements include any plans or intentions to improve the number and quality of supplier and smelter response rates and steps we intend to take to mitigate risk in our supply chain. These forward-looking statements involve risks and uncertainties that could cause actual results to differ materially from those projected. In particular, the Company’s risk mitigation and improvement plans may be affected by: (a) changes in global regulations related to the extraction of and disclosure obligations related to conflict minerals; (b) the ability of our suppliers and smelters to provide accurate information in response to our requests; (c) the availability of alternate sources of materials necessary to the functionality or production of our products on commercially reasonable terms or at all; (d) the ability of certified smelters to meet demand for raw materials; and (e) limits on our ability to unilaterally influence supplier behavior. These forward- looking statements are made as of the date hereof and we assume no obligation to update such statements, except as required by law.

The statements included in this CMR are based on the Reasonable Country of Origin Inquiry process and due diligence performed in good faith by Glaukos and are based on the information available at the time of such inquiry. A number of factors could introduce errors or otherwise affect the accuracy of these statements. These factors include, but are not limited to: (i) gaps in supplier or smelter data, (ii) errors or omissions by suppliers or smelters, (iii) uncertainty or varied interpretations of the disclosure requirements described in the SEC rules, (iv) inaccuracies by our suppliers in reporting the conflict minerals necessary to the functionality or manufacturing of our products, (v) the unfamiliarity of some suppliers and smelters with the diligence process and information required to be provided, which could lead to inaccurate or incomplete responses, (vi) timeliness of data received from our suppliers, (vii) information that is in the public domain may not be discovered despite having conducted a reasonable search, (viii) errors in publicly available information, (ix) language barriers or errors in translation could lead to inaccurate information, (x) oversights or errors in conflict-free smelter audits, (xi) materials sourced from the Covered Countries could be inaccurately declared as sourced from outside the Covered Countries, (xii) illegally tagged Conflict Minerals could be introduced into the supply chain without our knowledge or the knowledge of our suppliers, (xiii) difficulties obtaining information from companies that are no longer in business, and (xiv) smuggling of Conflict Minerals outside the Covered Countries, which could make identification of their place of origin more difficult.

Introduction

Glaukos is an ophthalmic pharmaceutical and medical technology company focused on developing and commercializing novel therapies for the treatment of glaucoma, corneal disorders, and retinal disease. We first developed Micro-Invasive Glaucoma Surgery ("MIGS") as an alternative to the traditional glaucoma treatment paradigm, launching our first MIGS device commercially in 2012, and continue to develop and advance a portfolio of novel, dropless platform technologies designed to meaningfully advance the standard of care and improve outcomes for patients suffering from chronic, sight-threatening diseases across the areas of glaucoma, corneal disorders such as keratoconus and dry eye, and retinal diseases. We have designed commercial and development-stage solutions to provide ophthalmologists with new treatment alternatives.

This CMR relates to the process undertaken for Glaukos products that were manufactured, or contracted to be manufactured, for commercial use during calendar year 2025 and that contain Conflict Minerals.

Executive Summary

We performed a Reasonable Country of Origin Inquiry (“RCOI”) on our suppliers, including those we believe provided materials or components containing 3TGs necessary to the manufacturing of our commercial products during calendar year 2025. Our due diligence process included contacting each supplier requesting conflict minerals data using the Conflict Minerals Reporting Template (“CMRT”); 90% of these suppliers responded to our inquiries. Our suppliers identified 337 valid smelters and refineries (“Smelters”). Of these 337 Smelters, we identified 48 as sourcing (or there was a reason to believe they may be sourcing) from the Covered Countries. Our due diligence review indicated that 32 of these Smelters have been audited and recognized as conformant to the Responsible Minerals Assurance Process (“RMAP”). This process was in accordance with the OECD Due Diligence Guidance for Responsible Supply Chains of Minerals from Conflict-Affected and High-Risk Areas (“OECD Guidance”). Glaukos conducted risk mitigation on the remaining 16 Smelters.

Company Management Systems

Glaukos established strong management systems based on Step 1 of the OECD Guidance.

· Step 1A - Adopt, and clearly communicate to suppliers and the public, a company policy for the supply chain of minerals originating from conflict-affected and high-risk areas. We have adopted a conflict minerals policy as part of our Supplier Code of Conduct and Conflict Minerals Policy that is publicly available on our Investor website under the heading “Corporate Responsibility” at http://investors.glaukos.com. The Supplier Code of Conduct and Conflict Minerals Policy is communicated to our suppliers as part of the RCOI process.

· Step 1B - Structure internal management to support supply chain due diligence. We maintain a cross- functional internal team to support our supply chain due diligence efforts. This team reports its findings to a senior member of the supply chain management organization.

· Step 1C - Establish a system of transparency, information collection and control over the supply chain. We implemented a detailed process to collect required supplier and smelter RCOI and due diligence data. Full details on the supply chain data gathering are included in the RCOI and due diligence sections of this Report.

· Step 1D - Strengthen company engagement with suppliers. We engage directly with suppliers during the RCOI process. Additionally, we endeavor to include updated the terms and conditions in the agreements that will apply to our suppliers on a prospective basis to require them to work with us to source materials from smelters that, if sourcing from conflict-affected or high-risk areas, are either

conformant with the RMI’s RMAP assessment protocols (“RMAP Conformant”) or are working towards RMAP Conformance.

· Step 1E - Establish a company level grievance mechanism. Our employees and suppliers can anonymously report a violation of our policies according to our Code of Business Conduct and Ethics, ask questions or voice concerns by calling 1-844-462-5721, or online at www.glaukos.ethicspoint.com.

Reasonable Country of Origin Inquiry (RCOI)

We designed our RCOI process in accordance with Step 2A and 2B of the OECD Guidance. Our RCOI process involved two stages:

· Stage 1 - Supplier RCOI (Step 2A of the OECD Guidance)

· Stage 2 - Smelter RCOI (Step 2B of the OECD Guidance)

For the 2025 reporting period, Glaukos’ RCOI process was executed by Claigan Environmental Inc. (“Claigan”).

Supplier RCOI

We designed our supplier RCOI process to identify the smelters in our supply chain. Our supplier RCOI process for the 2025 reporting period included:

· developing a list of suppliers providing components for our commercial products

· contacting each supplier and requesting Conflict Minerals data using the industry-standard CMRT

· reviewing supplier responses for accuracy and completeness

· aggregating supplier-provided smelters into a single unique list of smelters meeting the definition of a smelter under one of three industry-recognized audit protocols

· reviewing the final smelter list (and comparing it to industry peers) to determine if we reasonably identified all the smelters in our supply chain.

Through the supplier RCOI process, we identified 337 Smelters in our supply chain.

Smelter RCOI

Due to the overlap between smelter RCOI and smelter due diligence, the smelter RCOI process is summarized in the due diligence section of this report.

Due Diligence

Glaukos’s due diligence process was designed in accordance with the applicable sections of Steps 2, 3, and 4 of the OECD Guidance.

For the 2025 reporting period, Glaukos’s smelter RCOI and due diligence process were executed by Claigan.

Smelter RCOI and Due Diligence

Glaukos’ smelter RCOI and due diligence processes were designed to meet the criteria of Step 2 of the OECD Guidance.

We engaged with each Smelter identified in our supply chain to determine whether or not they sourced from the Covered Countries. For Smelters that confirmed, either directly or through industry associations, that they did not source from the Covered Countries but who were not recognized as RMAP Conformant, we reviewed publicly available information to determine whether there was any evidence that contradicted the Smelter’s declaration. In doing so, we reviewed sources such as NGO publications, the most recent United Nations Group of Experts reports on the DRC, and performed public internet searches.

If Smelters did not respond to our inquiry, we reviewed the same publicly available sources to determine whether there was reason to believe the Smelter may have sourced from the Covered Countries during the reporting period.

We categorize Smelters that are sourcing (or that we have reason to believe may be sourcing) from the Covered Countries and not currently RMAP Conformant as high-risk. We plan to consider options to transition to smelters that reflect Glaukos’ company values, which may include engaging with our suppliers who source from these high-risk smelters or considering alternative suppliers for the relevant components.

Our suppliers identified 337 unique Smelters, of which 48 Smelters source, or there is a reason to believe they may source, from the Covered Countries. We determined that 32 of these Smelters have been audited and recognized as RMAP Conformant. Glaukos conducted risk mitigation on the remaining 16 Smelters.

Risk Mitigation

Glaukos conducted risk mitigation on 16 Smelters that were not recognized as RMAP Conformant and were sourcing (or there is a reason to believe they may be sourcing) from the DRC or surrounding countries. Glaukos’ risk mitigation was designed in accordance with Step 3B of the OECD Guidance and will be reported to the Company’s Management Compliance Committee in accordance with Step 3A of the OECD Guidance.

As part of our risk mitigation process, we performed additional due diligence to determine if there was any reason to believe the smelters directly or indirectly financed or benefited armed groups in the DRC or adjoining countries. We also attempted to verify with internal stakeholders and relevant suppliers whether 3TGs from the Smelter in question were actually in Glaukos’ supply chain during the 2025 reporting period, and considered whether we could find alternative products or suppliers. Finally, we have engaged directly with our suppliers to encourage them to source from Smelters that are audited and recognized as RMAP Conformant. These Smelters are scheduled to be re-visited in the 2026 reporting period.

During the due diligence process, Glaukos found that one of the 16 identified high risk Smelters was RMAP Conformant for the entirety of the reporting period in question and was removed from the RMAP Conformant list at the beginning of 2026. Around the same time, it was announced that the Smelter had ceased operations. Another of the 16 identified high risk Smelters was RMAP Conformant for the majority of the reporting period in question and was removed from the RMAP Conformant list in August 2025. Therefore, this facility was considered low risk for most of the reporting period in question. If this Smelter does not re-engage with the RMAP, Glaukos will follow-up with suppliers regarding this Smelter during the 2026 reporting period.

Risk Mitigation Improvement Plan

Glaukos is committed to continuous improvement in our due diligence process to further mitigate the risk that the 3TG materials in our products could directly or indirectly benefit or finance armed groups in the Covered Countries. As part of our efforts to mitigate this risk, new or renewed supplier contracts will require suppliers to substantially comply with our Supplier Code of Conduct and Conflict Minerals Policy, and provide information that will allow us to evaluate their Conflict Mineral sourcing status. Additionally, we are continuing to engage with and educate our suppliers to increase supplier response rates and improve the timeliness, accuracy and comprehensiveness of the supplier survey responses we receive. We are also continuing to work with our suppliers to encourage them to source from RMAP Conformant smelters when sourcing material from the Covered Countries.

Smelters and Refineries

* Certain of our suppliers reported the presence of entities that were sanctioned by the United States Department of Treasury, Office of Foreign Assets Control, consisting of JSC Uralelectromed and African Gold Refinery. Because of the over-inclusive nature of the industry CMRT information collection process, and the nature of the supply chains and goods, we are unable to confirm this, or any, Smelter is or was active in our supply chain.

Forty-eight of the 337 unique Smelters identified during our RCOI either declared that they were sourcing, or there was reason to believe may be sourcing, from the Covered Countries. Based on the Smelters’ disclosures and the publicly available information, we have reason to believe these Smelters may be sourcing from the following Covered Countries: The Democratic Republic of the Congo, Rwanda, Burundi, Uganda, Tanzania, Angola, and Zambia. Our due diligence review indicated that 32 of these Smelters have been audited and recognized as RMAP Conformant.