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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Name of Issuer)

(Title of Class of Securities)

(CUSIP Number)

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

X0202 SCHEDULE 13D/A 0001224962 XXXXXXXX LIVE 2 Ordinary Shares, nominal value EUR 0.01 per share 08/26/2026 false 0001809196 N44445109 Immatics N.V. PAUL EHRLICH-STRASSE 15 TUBINGEN 2M 72076 Alexander Rakitin (646) 205-5340 51 Astor Pl, 10th FL New York NY 10003 0001224962 N Perceptive Advisors LLC b AF Y DE 0 11418016 0 11418016 11418016 N 7.6 IA 0001249675 N Perceptive Life Sciences Master Fund, Ltd. b WC N E9 0 11418016 0 11418016 11418016 N 7.6 CO 0001164426 N Joseph Edelman b AF N 0 11418016 0 11418016 11418016 N 7.6 IN Ordinary Shares, nominal value EUR 0.01 per share Immatics N.V. PAUL EHRLICH-STRASSE 15 TUBINGEN 2M 72076 The shares of Ordinary Shares set forth below in Item 5(c) of this Amendment No. 2 to Schedule 13D were acquired with working capital of Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund"). The information set forth in Item 6 below in this Amendment No. 2 to Schedule 13D is incorporated by reference. The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference. The percentages set forth in row 13 are based on 149,635,893 Ordinary Shares outstanding, as reported by the Issuer in its prospectus filed pursuant to Rule 424(b)(2) with the Securities and Exchange Commission on August 25, 2026, and assumes the exercise of vested stock options issued to Adam Stone in connection with his service on the Issuer's board of directors. The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference. Adam Stone, the Chief Investment Officer of Perceptive Advisors LLC ("Perceptive Advisor"), holds stock options for a total of 219,500 Ordinary Shares, of which 171,500 are currently exercisable, or exercisable within 60 days. Perceptive Advisors has the right to receive the director compensation provided in respect of Mr. Stone's board service through a partial management fee offset. The information set forth in Item 6 of this Amendment No. 2 is incorporated by reference to this Item 5(c). On August 26, 2026, the Master Fund purchased 863,060 Ordinary Shares at a price per share of $8.69 in the Issuer's underwritten offering. Except as described herein, none of the Reporting Persons has effected any transaction in the Ordinary Shares in the past 60 days. Perceptive Advisors LLC /s/ Joseph Edelman Joseph Edelman, Managing Member 08/27/2026 Perceptive Life Sciences Master Fund, Ltd. /s/ Joseph Edelman Joseph Edelman, Managing Member 08/27/2026 Joseph Edelman /s/ Joseph Edelman Joseph Edelman 08/27/2026