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Exhibit 10.48

CERTAIN INFORMATION IN THIS EXHIBIT MARKED [***] HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT IS PRIVATE OR CONFIDENTIAL.

AMENDMENT TO RESEARCH COLLABORATION AGREEMENT (“Amendment”)

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This Amendment is dated 08 August 2024 (“Effective Date”)

Between:

(1)COMPASS PATHFINDER LIMITED, a company incorporated in England and Wales under company number 10229259, with its registered offices at 3rd Floor, 1 Ashley Road, Altrincham, Cheshire, WA14 2DT, United Kingdom (“Compass”); and

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(2)TMS NEUROHEALTH CENTERS, INC., a Delaware corporation with an address at 8401 Greensboro Drive, Suite 425, Tysons Corner, VA 22102 and its affiliated medical practices (together “GTMS”),

each a “Party” and together the “Parties”.

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WHEREAS:

(A)The Parties entered into a Research Collaboration Agreement as of December 15, 2023 (“Agreement”) which included a Collaboration Plan (as defined in the Agreement);

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(B)The Steering Committee (as defined in the Agreement) has agreed to certain amendments to the deliverables and research activities contained in the Collaboration Plan; and

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(C)The Parties now wish to memorialize such amendments by updating the Collaboration Plan.

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NOW, THEREFORE, in consideration of the foregoing and for valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Compass and GTMS, intending to be legally bound, agree as follows:

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1.Definitions

Unless otherwise defined in this Amendment, all capitalized terms used in this Amendment shall have the meaning ascribed to them in the Agreement.

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2.Collaboration Plan

2.1The deliverable for the Milestone 0 [***] in the Compensation Table contained in the Collaboration Plan shall be revised to reflect the following:

[***]

2.2The activity description for Milestone 1 in the Compensation Table contained in the Collaboration Plan shall be revised to include the following:

●[***]

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3.No Further Amendments

Except as expressly modified herein, there are no further amendments to the Agreement, which remains in full force and effect.

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IN WITNESS THEREOF, the Parties hereto have executed this Amendment as of the Effective Date by proper persons thereunto duly authorized.

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COMPASS PATHFINDER LIMITED

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/s/Kabir Nath

CEO

8/8/2024

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GTMS

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/s/ Geoffrey Grammer

Chief Medical Officer

8/8/2024