Exhibit 21.1
Significant Subsidiaries of QXO, Inc.
The following table sets forth, as of May 15, 2026, the Registrant’s significant subsidiaries and their jurisdiction of incorporation. The Registrant owns 100% of the voting securities of each of the subsidiaries listed below. There are no subsidiaries not listed in the table, which would, in the aggregate, be considered significant.
| Subsidiaries | Jurisdiction of Incorporation | |
| QXO Building Products, Inc. | Delaware | |
| Beacon Sales Acquisition, Inc. | Delaware | |
| Kodiak Building Partners, Inc. | Delaware | |
| American Builders Supply, Inc. | Delaware | |
| Carpenter Contractors of America, Inc. | Illinois |