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Exhibit 32.1 
CERTIFICATION PURSUANT TO 
18 U.S.C. SECTION 1350, 
AS ADOPTED PURSUANT TO 
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 
The certification set forth below is being submitted in connection with the Quarterly Report on Form 10-Q (the “Report”) of Ultra Clean Holdings, Inc. (the “Company”) for the purpose of complying with Rule 13a-14(b) or Rule 15d-14(b) of the Securities Exchange Act of 1934 (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code. 
Clarence L Granger, Interim Chief Executive Officer, and Sheri Savage, Chief Financial Officer of the Company, each certifies that, to the best of his or her knowledge: 
(1)the Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and 
(2)the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company. 
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Date: July 29, 2025  |  | 
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| /s/ CLARENCE L. GRANGER |  | 
| Clarence L. Granger |  | 
| Interim Chief Executive Officer |  | 
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Date: July 29, 2025  |  | 
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| /s/ SHERI SAVAGE |  | 
| Sheri Savage |  | 
| Chief Financial Officer |  |