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SCHEDULE 13D/A 0000905718-21-001150 0001279191 XXXXXXXX LIVE 6 Common Stock, Par Value $0.0001 Per Share. 03/27/2025 false 0001853816 249845108 Dermata Therapeutics, Inc. 3525 Del Mar Heights Rd., #322 San Diego CA 92130 Gerald T. Proehl (973) 701-2431 President and Chief Executive Officer 3525 Del Mar Heights Rd., #322 San Diego CA 92130 0001279191 N PROEHL GERALD T PF N X1 804098.00 0.00 804098.00 0.00 804098.00 N 7.8 IN See Item 5 for additional information. 0001877913 N Proehl Investment Ventures LLC WC N CA 799624.00 0.00 799624.00 0.00 799624.00 N 7.8 IN See Item 5 for additional information. Common Stock, Par Value $0.0001 Per Share. Dermata Therapeutics, Inc. 3525 Del Mar Heights Rd., #322 San Diego CA 92130 This Amendment No. 6 (this "Amendment") amends and supplements the Schedule 13D filed on behalf of the Reporting Persons with the Securities and Exchange Commission on August 27, 2021, as amended on April 25, 2022, January 13, 2023, March 30, 2023, January 23, 2025 and February 13, 2025 (collectively, the "Schedule 13D"). Except as specifically provided herein, this Amendment does not modify or amend any of the information previously reported in the Schedule 13D. Capitalized terms used and not otherwise defined herein shall have the meanings ascribed to such terms in the Schedule 13D. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable. The information contained in rows 7, 8, 9, 10, 11 and 13 of the cover pages of this Schedule 13D and the information set forth in or incorporated by reference in Item 2 and Item 3 of the Schedule 13D is hereby incorporated by reference in its entirety into this Item 5. As of the date hereof, Mr. Proehl may be deemed to beneficially own an aggregate of 804,098 shares of Common Stock reported herein as follows: (i) 247 shares of Common Stock and stock options to purchase 2,777 shares of Common Stock held directly by Mr. Proehl; (ii) 799,508 shares of Common Stock and warrants to purchase up to 116 shares of Common Stock held directly by Proehl Investment Ventures LLC ("PIV"); (iii) 855 shares of Common Stock and warrants to purchase up to 595 shares of Common Stock held in the aggregate by certain trusts (the "Trusts") for which Mr. Proehl is trustee. Mr. Proehl's reported ownership excludes (i) 50,556 shares of Common Stock underlying stock options held by Mr. Proehl that will not vest as to such shares of Common Stock within sixty (60) days of the date hereof, and (ii) 787,402 shares of Common Stock underlying a warrant that is not exercisable within sixty (60) days of the date hereof. As a result of the foregoing, for purposes of Rule 13d-3 under the Securities Exchange Act of 1934, as amended, Mr. Proehl may be deemed to beneficially own 7.8% of the Common Stock of the Issuer outstanding as of the date hereof (based on 10,265,118 shares of Common Stock outstanding as of March 27, 2025 based on information obtained from the Issuer). As of the date hereof, PIV may be deemed to be the beneficial owner of an aggregate of 799,624 shares of Common Stock reported herein as follows: (i) 799,508 shares of Common Stock and (ii) warrants to purchase up to 116 shares of Common Stock. As a result of the foregoing, for purposes of Rule 13d-3 under the Securities Exchange Act of 1934, as amended, PIV may be deemed to beneficially own 7.8% of the Common Stock of the Issuer outstanding as of the date hereof (based on 10,265,118 shares of Common Stock outstanding as of March 27, 2025 based on information obtained from the Issuer). As of the date hereof, Mr. Proehl may be deemed to be the beneficial owner of an aggregate of 803,751 shares of Common stock, all of which he has sole voting and dispositive power. As of the date hereof, PIV may be deemed to be the beneficial owner of an aggregate of 799,624 shares of Common stock, for all of which voting and dispositive power is held by Mr. Proehl, as PIV's managing member. During the sixty (60) days on or prior to March 27, 2025, there were no purchases or sales of shares of Common Stock, or securities convertible into or exchangeable for shares of Common Stock, by the Reporting Persons or any person or entity for which the Reporting Persons possess voting or dispositive control over the securities thereof. None. Not applicable. PROEHL GERALD T /s/ Gerald T. Proehl Gerald T. Proehl 04/03/2025 Proehl Investment Ventures LLC /s/ Gerald T. Proehl Gerald T. Proehl, Managing Member 04/03/2025