EX-FILING FEES

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Exhibit 107

N/A

S-3ASR

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Omeros Corporation

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security
Type

Security Class
Title

Fee
Calculation
or Carry
Forward
Rule

Amount
Registered

Proposed
Maximum
Offering
Price Per
Unit

Maximum
Aggregate
Offering
Price

Fee Rate

Amount of
Registration
Fee

Carry
Forward
Form Type

Carry
Forward
File
Number

Carry
Forward
Initial
Effective
Date

Filing Fee
Previously
Paid in
Connection
with
Unsold
Securities
to be
Carried
Forward

Newly Registered Securities

Fees to be Paid

Equity

Common Stock, par value $0.01 per share

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Equity

Preferred Stock, par value $0.01 per share

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Debt

Debt Securities

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Other

Depositary Shares⁽³⁾

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Other

Warrants⁽⁴⁾

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Other

Subscription Rights

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Other

Units⁽⁵⁾

Rule 456(b) and Rule 457(r)⁽¹⁾

(2)

(2)

(2)

(1)

(1)

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

(2)

(2)

(1)

Total Fees Previously Paid

—

Total Fee Offsets

$23,956.08⁽²⁾

Net Fee Due

—

Table 2: Fee Offset Claims and Sources

Registrant or Filer Name

Form or Filing Type

File Number

Initial Filing Date

Filing Date

Fee Offset Claimed

Security Type Associated with Fee Offset Claimed

Security Title Associated with Fee Offset Claimed

Unsold

Securities

Associated

with Fee

Offset

Claimed

Unsold

Aggregate

Offering

Amount

Associated with

Fee Offset

Claimed

Fee Paid with

Fee Offset

Source

Rules 457(b) and 0-11(a)(2)

Fee Offset Claims

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Fee Offset Sources

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Rule 457(p)

Fee Offset Claims

Omeros Corporation

Form S-3

333-268269

November 9, 2022

$23,956.08⁽¹⁾

Unallocated

(1)

(1)

$258,425,901.70

Fee Offset Sources

Omeros Corporation

Form S-3

333-268269

November 9, 2022

(1)

(1)

In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended (the “Securities Act”), Omeros Corporation (the “Registrant”) is deferring payment of all of the registration fees associated with the registration of the offer and sale of the aforementioned securities, except for $23,956.08 that the Registrant is entitled to offset pursuant to Rule 457(p) for fees paid with respect to unsold securities registered pursuant to the Registration Statement on Form S-3, File No. 333-268269, filed by the registrant on November 9, 2022 having an aggregate initial offering price of $300,000,000 (the “Prior Registration Statement”). The Registrant has terminated or completed any offerings that included the unsold securities under the Prior Registration Statement. In connection with the securities offered hereby, except for the application of these previously-paid fees, the Registrant will pay registration fee on a “pay-as-you-go” basis pursuant to Rule 456(b).

(2)

An indeterminate number and aggregate initial offering price of securities of each identified class are being registered as may from time to time be offered at indeterminate prices, including an indeterminate number or amount of securities that may be issued upon the exercise, settlement, exchange or conversion of securities offered hereunder. Separate consideration may or may not be received for securities that are issuable on exercise, settlement, exchange or conversion of other securities. In addition, pursuant to Rule 416 under the Securities Act, the securities being registered hereunder include such indeterminate number of additional securities as may be issuable as a result of stock splits, stock dividends or similar transactions.

(3)	Each depositary share will be issued under a depositary agreement and will be evidenced by a depositary receipt.

(4)	Includes warrants to purchase common stock, preferred stock or debt securities.

(5)	Each unit will represent an interest in two or more securities registered under this Registration Statement, which may or may not be separable from one another.