73 High Street

Buffalo, NY 14203

June 8, 2021

VIA EDGAR AND EMAIL

Alan Campbell

Division of Corporation Finance, Office of Life Sciences

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549-4561

Registration Statement on Form S-4

File No. 333-253111


Acceleration Request

Dear Mr. Campbell:

 

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned, on behalf of Cleveland BioLabs, Inc. (the “Company”), respectfully requests that the effective date for the Registration Statement referred to above be accelerated so that it will be declared effective at 4:30 p.m. Eastern Time on June 10, 2021, or at such later time as the Company, acting through its counsel, McGuireWoods LLP, may request via a telephone call to the staff of the Division of Corporation Finance of the Securities and Exchange Commission.

 

Please contact David S. Wolpa at (704) 343-2185 or DWolpa@mcguirewoods.com with any questions you may have concerning this letter, or if you require any additional information. Please notify Mr. Wolpa when this request for acceleration of effectiveness of the Registration Statement has been granted.

 

	Very truly yours,
	/s/ Christopher Zosh
	Christopher Zosh Vice President of Finance