Exhibit 107
Calculation of Filing Fee Table
Registration Statement on Form S-1
(Form Type)
LYRA THERAPEUTICS, INC.
(Exact Name of Registrant as Specified in its Charter)
Table 1: Newly Registered and Carry Forward Securities
| Security Type | Security Class Title | Fee Calculation or Carry Forward Rule | Amount Registered | Proposed Maximum Offering Price Per Unit(1) | Maximum Aggregate Offering Price(1) | Fee Rate | Amount of Registration Fee | Carry Forward Form Type | Carry Forward File Number | Carry Forward Initial Effective Date | Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward | |||||||||||||
| Fees to Be Paid | Equity | Common Stock, par value per share | 457(c) | 846,744 (2) | $8.185 | $6,930,599.64 | 0.00015310 | $1,061.08 | ||||||||||||||||
| Fees Previously Paid | — | — | — | — | — | — | — | — | — | — | — | |||||||||||||
| Carry Forward Securities | — | — | — | — | — | — | — | — | — | — | ||||||||||||||
| Total Offering Amounts | $6,930,599.64 | $1,061.08 | ||||||||||||||||||||||
| Total Fees Previously Paid | — | |||||||||||||||||||||||
| Total Fee Offsets | — | |||||||||||||||||||||||
| Net Fee Due | $1,061.08 | |||||||||||||||||||||||
| (1) | Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457(c) of the Securities Act, on the basis of the average of the high and low prices for a share of the registrant’s common stock as reported on the Nasdaq Capital Market on July 18, 2025, which date is a date within five business days prior to the filing of this registration statement. | 
| (2) | Consists of shares of our common stock issuable to the selling securityholders upon exercise of warrants to purchase common stock. Pursuant to Rule 416 under the Securities Act of 1933, as amended, the shares of common stock being registered hereunder include such indeterminate number of shares of common stock as may be issuable with respect to the shares of common stock being registered hereunder as a result of stock splits, stock dividends or similar transactions. |