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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
 
We consent to the incorporation by reference in the Registration Statement (Form S-8 filed on May 30, 2014) pertaining to the 2014 Omnibus Incentive Plan of NxStage Medical, Inc. of our reports dated March 3, 2014, with respect to the consolidated financial statements of NxStage Medical, Inc. and the effectiveness of internal control over financial reporting of NxStage Medical, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2013, filed with the Securities and Exchange Commission.
 
 /s/ Ernst & Young LLP
 
Boston, Massachusetts
May 30, 2014