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Exhibit T3A.18

Number 571411
Duplicate for the File
 
Certificate of Incorporation
 
I hereby certify that
 
AMRYT RESEARCH LIMITED
 
is this day incorporated under
the Companies Act 2014,
and that the company is
a Private Company Limited by Shares.
 
Given under my hand at Dublin, this
Monday, the 9th day of November, 2015

/s/ Registrar
 
for Registrar of Companies