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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox not checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)




SCHEDULE 13D/A 0001352546 XXXXXXXX LIVE 4 Common Stock, par value $0.0001 per share 02/09/2026 false 0001739174 09090D509 BiomX Inc. 850 NEW BURTON ROAD SUITE 201 DOVER DE 19904 Deerfield Management Company 212-551-1600 345 Park Avenue South, 12th Floor New York NY 10010 Jonathan D. Weiner, Esq. 212-940-8800 Katten Muchin Rosenman LLP 50 Rockefeller Plaza New York NY 10020 Mark D. Wood, Esq. 212-940-8800 Katten Muchin Rosenman LLP 50 Rockefeller Plaza New York NY 10020 0001815437 N Deerfield Private Design Fund V, L.P. b WC N DE 0.00 494267.00 0.00 494267.00 494267.00 N 9.99 PN The number of shares of Common Stock beneficially owned by the Reporting Person consists of (i) 65,635 shares of Common Stock, (ii) an aggregate of 252,406 shares of Common Stock issuable upon conversion of 47,957 shares of Series X Preferred Stock (subject to the Beneficial Ownership Limitation (as defined below)) and (iii) an aggregate of 176,226 shares of Common Stock underlying warrants that are currently exercisable (subject to the Beneficial Ownership Limitation). The terms of the Series X Preferred Stock and provisions of the warrants restrict the conversion of such shares or the exercise of such warrants, as applicable, to the extent that, upon such conversion or exercise, the number of shares of Common Stock then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) "group" would exceed 9.99% of the total number of shares of Common Stock then outstanding (the "Beneficial Ownership Limitation"). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of Common Stock issuable upon conversion of Series X Preferred Stock and the exercise of such warrants to the extent that upon such conversion or exercise the number of shares beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Beneficial Ownership Limitation. 0001876688 N Deerfield Mgmt V, L.P. b AF N DE 0.00 494267.00 0.00 494267.00 494267.00 N 9.99 PN Comprised of shares of Common Stock held by, and shares of Common Stock issuable upon exercise of warrants or that will become issuable upon conversion of shares of Series X Preferred Stock held by, Deerfield Private Design Fund V, L.P. See Footnote 1. 0001780064 N Deerfield Healthcare Innovations Fund II, L.P. b WC N DE 0.00 494267.00 0.00 494267.00 494267.00 N 9.99 PN The number of shares of Common Stock beneficially owned by the Reporting Person consists of (i) 65,635 shares of Common Stock, (ii) an aggregate of 252,406 shares of Common Stock issuable upon conversion of 47,957 shares of Series X Preferred Stock (subject to the Beneficial Ownership Limitation (as defined below)) and (iii) an aggregate of 176,226 shares of Common Stock underlying warrants that are currently exercisable (subject to the Beneficial Ownership Limitation). The terms of the Series X Preferred Stock and provisions of the warrants restrict the conversion of such shares or the exercise of such warrants, as applicable, to the extent that, upon such conversion or exercise, the number of shares of Common Stock then beneficially owned by the holder and its affiliates and any other person or entities with which such holder would constitute a Section 13(d) "group" would exceed 9.99% of the total number of shares of Common Stock then outstanding (the "Beneficial Ownership Limitation"). Accordingly, notwithstanding the number of shares reported, the reporting person disclaims beneficial ownership of the shares of Common Stock issuable upon conversion of Series X Preferred Stock and the exercise of such warrants to the extent that upon such conversion or exercise the number of shares beneficially owned by all reporting persons hereunder, in the aggregate, would exceed the Beneficial Ownership Limitation. 0001665736 N Deerfield Mgmt HIF II, L.P. b AF N DE 0.00 494267.00 0.00 494267.00 494267.00 N 9.99 PN Comprised of shares of Common Stock held by, and shares of Common Stock issuable upon exercise of warrants or that will become issuable upon conversion of shares of Series X Preferred Stock held by, Deerfield Healthcare Innovations Fund II, L.P. See Footnote 3. 0001009258 N Deerfield Management Company, L.P. b AF N DE 0.00 989056.00 0.00 989056.00 989056.00 N 9.99 PN Comprised of (i) shares of Common Stock held by, and shares of Common Stock issuable upon exercise of warrants or that will become issuable upon conversion of shares of Series X Preferred Stock held by, Deerfield Private Design Fund V, L.P. and Deerfield Healthcare Innovations Fund II, L.P (see Footnotes 1 and 3); and (ii) 522 shares of Common Stock issuable upon exercise of options held by Jonathan Leff for the benefit, and at the direction, of Deerfield Management Company, L.P. 0001352546 N James E. Flynn b AF N X1 0.00 989056.00 0.00 989056.00 989056.00 N 9.99 IN Comprised of (i) shares of Common Stock held by, and shares of Common Stock issuable upon exercise of warrants or that will become issuable upon conversion of shares of Series X Preferred Stock held by, Deerfield Private Design Fund V, L.P. and Deerfield Healthcare Innovations Fund II, L.P (see Footnotes 1 and 3); and (ii) 522 shares of Common Stock issuable upon exercise of options held by Jonathan Leff for the benefit, and at the direction, of Deerfield Management Company, L.P. Common Stock, par value $0.0001 per share BiomX Inc. 850 NEW BURTON ROAD SUITE 201 DOVER DE 19904 This Amendment No. 4 (this "Amendment") to Schedule 13D amends the Schedule 13D filed by (i) Deerfield Private Design Fund V, L.P. ("Deerfield Private Design V"), (ii) Deerfield Mgmt V, L.P. ("Deerfield Mgmt V") (iii) Deerfield Healthcare Innovations Fund II, L.P. ("Deerfield HIF II"), (iv) Deerfield Mgmt HIF II, L.P. ("Deerfield Mgmt HIF II"), (v) Deerfield Management Company, L.P. ("Deerfield Management"), and (vi) James E. Flynn, a natural person ("Flynn," and collectively with Deerfield Management, Deerfield Private Design V, Deerfield Mgmt V, Deerfield HIF II, Deerfield Mgmt HIF II, the "Reporting Person"), with respect to the Common Stock of BiomX Inc., as previously amended by Amendment Nos. 1, 2 and 3 thereto (such Schedule 13D, as so amended, the "Schedule 13D"). Deerfield Private Design V and Deerfield HIF II are referred to herein, collectively, as the "Funds" and each as a "Fund." Capitalized terms used but not otherwise defined in this Amendment have the meanings ascribed to them in the Schedule 13D. Item 4 of the Schedule 13D is hereby amended by adding the following: Jonathan Leff, a partner of Deerfield Management, resigned from the Issuer's board of directors effective February 9, 2026. Items 5(a), (b) and (c) of the Schedule 13D are hereby amended and restated in their entirety as follows: (1) Deerfield Mgmt V, L.P. Number of shares: 494,267 (comprised of shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants, in each case, held by Deerfield Private Design Fund V, L.P.) Percentage of Shares: 9.99%* (2) Deerfield Private Design Fund V, L.P. Number of shares: 494,267 (comprised of shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants,) Percentage of Shares: 9.99%* (3) Deerfield Mgmt HIF II, L.P., L.P. Number of shares: 494,267 (comprised of shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants, in each case, held by Deerfield Healthcare Innovations Fund II, L.P.) Percentage of Shares: 9.99%* (4) Deerfield Healthcare Innovations Fund II, L.P. Number of shares: 494,267 (comprised of shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants) Percentage of Shares: 9.99%* (5) Deerfield Management Number of shares: 989,056 (comprised of (i) shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants, in each case, held by Deerfield Private Design Fund V, L.P. and Deerfield Healthcare Innovations Fund II, L.P. and (ii) shares of Common Stock issuable upon exercise of options held by Jonathan Leff for the benefit, and at the direction, of Deerfield Management) Percentage of Shares: 9.99%* (6) Flynn Number of shares: 989,056 (comprised of(i) shares of Common Stock, shares of Common Stock underlying Series X Preferred Stock and shares of Common Stock underlying warrants, in each case, held by Deerfield Private Design Fund V, L.P. and Deerfield Healthcare Innovations Fund II, L.P. and (ii) shares of Common Stock issuable upon exercise of options held by Jonathan Leff for the benefit, and at the direction, of Deerfield Management) Percentage of Shares: 9.99%* *Throughout this report, the percentage of outstanding shares of Common Stock beneficially owned by the Reporting Persons reflects (i) 1,593,516 shares of Common Stock outstanding as of February 3, 2026, as set forth in the Preliminary Proxy Statement of the Company, filed by the Company with the Securities and Exchange Commission on February 3, 2026, and also reflects the Beneficial Ownership Limitation. (1) Deerfield Mgmt V, L.P. Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 494,267 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 494,267 (2) Deerfield Private Design Fund V, L.P. Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 494,267 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 494,267 (3) Deerfield Mgmt HIF II, L.P. Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 494,267 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 494,267 (4) Deerfield Healthcare Innovations Fund II, L.P. Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 494,267 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 494,267 (5) Deerfield Management Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 989,056 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 989,056 (6) Flynn Sole power to vote or direct the vote: 0 Shared power to vote or direct the vote: 989,056 Sole power to dispose or to direct the disposition: 0 Shared power to dispose or direct the disposition: 989,056 Flynn is the sole manager of the general partner of each of Deerfield Mgmt V and Deerfield Mgmt HIF II and Deerfield Management. Deerfield Mgmt V is the general partner of Deerfield Private Design Fund V, L.P.; Deerfield Mgmt HIF II is the general partner of Deerfield Healthcare Innovations Fund II, L.P.; and Deerfield Management is the investment manager of each Fund. Each Fund purchases, holds and sells securities and other investment products. Schedule A hereto sets forth information regarding persons referred in Instruction C to Schedule 13D. No Reporting Person has effected any transactions in the Common Stock during the past 60 days. Deerfield Private Design Fund V, L.P. /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026 Deerfield Mgmt V, L.P. /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026 Deerfield Healthcare Innovations Fund II, L.P. /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026 Deerfield Mgmt HIF II, L.P. /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026 Deerfield Management Company, L.P. /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026 James E. Flynn /s/ Jonathan Isler Jonathan Isler, Attorney-in-Fact 02/11/2026