As filed with the U.S. Securities and Exchange Commission on August 5, 2026

Registration No. 333-

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8
REGISTRATION STATEMENT

UNDER
THE SECURITIES ACT OF 1933

MYOMO, INC.
(Exact Name of Registrant as Specified in Its Charter)

45 Blue Sky Dr., Suite 101
Burlington, Massachusetts 01803
(617) 996-9058
(Address of Registrant’s Principal Executive Offices)

Myomo, Inc. 2018 Stock Option and Incentive Plan
(Full title of the plan)

Paul R. Gudonis
President and Chief Executive Officer
Myomo, Inc.
45 Blue Sky Dr., Suite 101
Burlington, Massachusetts 01803
(617) 996-9058
(Name, address and telephone number, including area code, of agent for service)

Copies to:
Mitchell S. Bloom, Esq.
Catherine Magazu, Esq.
Goodwin Procter LLP
100 Northern Avenue
Boston, Massachusetts 02210
(617) 570-1000

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one):

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

EXPLANATORY NOTE

This Registration Statement on Form S-8 registers 1,833,000 additional shares of common stock, par value $0.0001 per share (“Common Stock”) of Myomo, Inc. (the “Company”) under the Myomo, Inc. 2018 Stock Option and Incentive Plan (as amended, the “Plan”). On June 25, 2026, at the Annual Meeting of Stockholders of the Company, the stockholders of the Company approved an amendment to the Plan to increase the number of shares available under the Plan by 1,833,000 shares. The amendment to the Plan was previously approved, subject to stockholder approval, by the board of directors of the Company. Accordingly, on June 25, 2026, the number of shares of Common Stock reserved and available for issuance under the Plan increased by 1,833,000 shares. Such additional shares are of the same class as other securities relating to the Plan for which the Registrant’s registration statements filed on Form S-8 on June 28, 2018 (Registration No. 333-225952), March 14, 2019 (Registration No. 333-230272), March 19, 2020 (Registration No. 333-237288), June 12, 2020 (Registration No. 333-239133), June 28, 2023 (Registration No. 333-272982), August 6, 2024 (Registration No. 333-281315), March 10, 2025 (Registration No. 333-285683) and March 9, 2026 (Registration No. 333-294148) are effective. The information contained in the Registrant’s registration statements on Form S-8 (Registration Nos. 333-225952, 333-230272, 333-237288, 333-239133, 333-272982, 333-281315, 333-285683 and 333-294148) is hereby incorporated by reference pursuant to General Instruction E.

Part II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 8. Exhibits.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the city of Cambridge, Commonwealth of Massachusetts, on the 5th day of August, 2026.

POWER OF ATTORNEY AND SIGNATURES

KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Paul R. Gudonis and David Henry, and each of them, as his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution in each of them, for him and in his name, place and stead, in any and all capacities, to sign for us and in our names in the capacities indicated below the Registration Statement on Form S-8 of Myomo, Inc., and any or all amendments (including post-effective amendments), and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in connection therewith and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them, or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement on Form S-8 has been signed by the following persons in the capacities and on the dates indicated.