United States securities and exchange commission logo August 23, 2023 John Morison Chief Financial Officer ONE STOP SYSTEMS, INC. 2235 Enterprise St., Suite 110 Escondido, CA 92029 Re: ONE STOP SYSTEMS, INC. Registration Statement on Form S-3 Filed August 18, 2023 File No. 333-274073 Dear John Morison: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Austin Pattan, Staff Attorney, at (202) 551-6756 or Matthew Derby, Legal Branch Chief, at (202) 551-3334 with any questions. Sincerely, Division of Corporation Finance Office of Technology