EXHIBIT 23.1
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| KPMG LLP | |
| Suite 1500 | |
| 550 South Hope Street | |
| Los Angeles, CA 90071-2629 |
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the registration statements (Nos. 333-181703, 333-196993, 333-205117, 333-218373, 333-219347, 333-236736, 333-259585, and 333-281803) on Form S-8 and (333-266306) on Form S-3 of our report dated February 26, 2026, with respect to the consolidated financial statements of Puma Biotechnology, Inc. and the effectiveness of internal control over financial reporting.

Los Angeles, California
February 26, 2026