Exhibit 21.1
Subsidiaries of the Registrant*
| Subsidiary | Jurisdiction of Incorporation | |
| Melinta Therapeutics, LLC | Delaware | |
| Melinta Subsidiary Corp. | Delaware | |
| Rempex Pharmaceuticals, Inc. | Delaware | |
| Targanta Therapeutics Corporation | Delaware | |
| CEM-102 Pharmaceuticals, Inc. | Delaware | |
| Cempra Pharmaceuticals, Inc. | Delaware |
| * | Inclusion on the list above is not an admission that any of the above entities, individually or in the aggregate, constitutes a significant subsidiary within the meaning of Rule 1-02(w) of Regulation S-X and Item 601(b)(21)(ii) of Regulation S-K. |