Exhibit 15.1

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Consent of Independent Registered Public Accounting Firm

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We hereby consent to the incorporation by reference in the Registration Statement on Form S­8 (No. 333-260920) of Evotec SE of our report dated April 25, 2022, relating to the consolidated financial statements which appears in this Form 20-F.

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/s/ BDO AG Wirtschaftsprüfungsgesellschaft

Frankfurt am Main, Germany

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April 26, 2022