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Exhibit 8.1

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Subsidiaries of the Registrant

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Jurisdiction of

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2022 Company

Subsidiaries of Registrant

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Incorporation

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voting rights

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(%)

Aptuit Global LLC, Princeton, US

    

Delaware

    

100.00

Aptuit (Verona) SRL, Verona, Italy

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Italy

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100.00

Aptuit (Oxford) Ltd., Abingdon, UK

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England

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100.00

Aptuit (Potters Bar) Ltd., Abingdon, UK

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England

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100.00

Cyprotex Discovery Ltd., Manchester, UK

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England

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100.00

Cyprotex Ltd., Manchester, UK

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England

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100.00

Cyprotex US, LLC., Framingham, US

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Delaware

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100.00

Evotec (France) SAS, Toulouse, France

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France

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100.00

Evotec ID (Lyon) SAS, Lyon, France

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France

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100.00

Evotec DS Germany GmbH, Halle, Germany

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Germany

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100.00

Evotec (Hamburg) GmbH, Hamburg, Germany

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Germany

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100.00

Evotec GT GmbH, Orth, Austria

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Austria

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100.00

Evotec (India) Private Ltd., Thane, India*

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India

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100.00

Evotec International GmbH, Hamburg, Germany

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Germany

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100.00

Evotec (Modena) Srl, Medolla, Italy

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Italy

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100,00

Evotec (München) GmbH, München, Germany

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Germany

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100.00

Evotec (UK) Ltd., Abingdon, UK

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England

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100.00

Evotec (US) Inc., Princeton, NJ, US

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Delaware

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100.00

Just-Evotec Biologics, Inc., Seattle, US

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Delaware

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100.00

Just-Evotec Biologics EU, Toulouse, France

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France

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100.00

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*

In voluntary liquidation.