Exhibit 31.1

Certification

I, Mark J. Foley, certify that:

1.     I have reviewed this Amendment No. 1 to Form 10-K/A of ZELTIQ Aesthetics, Inc.; and

2.    Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.