|  | (1) | Estimated
    in accordance with paragraphs (c) and (h) of Rule 457 under the Securities Act of 1933, as amended (the “Securities Act”),
    solely for purposes of calculating the registration fee. The price for Bone Biologics Corporation’s (the “Company”)
    common stock, $0.001 par value per share (“Common Stock”) being registered hereby is based on a price of $2.145 per share
    of Common Stock, which is the average of the high ($2.21) and low ($2.08) trading prices for a share of Common Stock on September
    19, 2025, as reported on the Nasdaq Stock Market. | 
  
    |  |  |  | 
  
    |  | (2) | Reflects
    5,000,000 additional shares (the “Additional Shares”) of Common Stock issuable under the Bone Biologics Corporation 2015
    Equity Incentive Plan (the “Plan”), as a result of an increase approved by the stockholders of the Company at its 2025
    Annual Meeting of Stockholders on May 30, 2025. The Additional Shares are in addition to the shares of Common Stock previously registered
    for issuance under the Plan pursuant to the Company’s Registration Statements on Form S-8 (File Nos. 333-212890 and 333-274545)
    filed with the Securities and Exchange Commission on August 3, 2016 and September 15, 2023, respectively. | 
  
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    |  | (3) | Pursuant
    to Rule 416(a) of the Securities Act, this Registration Statement also covers any additional shares of Common Stock that become issuable
    under the Plan by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the
    receipt of consideration that results in an increase in the number of outstanding shares of Common Stock. | 
  
    |  |  |  | 
  
    |  | (4) |  |