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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person:  After giving effect to the Reverse Stock Split (as defined below), Redmile Group, LLC's beneficial ownership of the Issuer's Common Stock, $0.0001 par value ("Common Stock") is comprised of 630,686 shares of Common Stock owned by certain private investment vehicles managed by Redmile Group, LLC (the "Redmile Funds"), including Redmile Biopharma Investments III, L.P. ("RBI III"). Subject to the Beneficial Ownership Blocker (as defined below), Redmile Group, LLC may also be deemed to beneficially own 1,957,432 shares of Common Stock issuable upon exercise of certain pre-funded warrants to purchase Common Stock (the "Warrants"). Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrant, and a holder of a Warrant does not have the right to exercise the Warrant held by such holder, to the extent that after giving effect to such issuance after exercise, the holder (together with the holder's affiliates, and any other persons acting as a group together with the holder or any of the holder's affiliates), would beneficially own in excess of 9.99% (the "Beneficial Ownership Limitation") of the number of shares of Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issued upon exercise of the Warrant (the "Beneficial Ownership Blocker"). The Beneficial Ownership Limitation may be changed at a holder's election upon 61 days' notice to the Issuer. The 1,765,303 shares of Common Stock reported as beneficially owned by Redmile Group, LLC in this Schedule 13G represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below), which includes 1,134,617 shares of Common Stock that could be issued upon exercise of certain of the Warrants under the Beneficial Ownership Blocker. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. Percentage based on: (i) 16,536,085 shares of Common Stock outstanding, which was calculated based on the amount of shares of Common Stock reported by the Issuer to be outstanding as of May 2, 2025 in its Form 10-Q for the quarterly period ended March 31, 2025 filed with the SEC on May 8, 2025 (the "Form 10-Q") and taking into account the 1-for-8 reverse stock split with respect to the Issuer's Common Stock that was effected on June 16, 2025 (the "Reverse Stock Split"), as reported by the Issuer in its Form 8-K filed with the SEC on June 17, 2025 (the "Form 8-K"); plus (ii) 1,134,617 shares of Common Stock issuable upon exercise of the Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.


SCHEDULE 13G




Comment for Type of Reporting Person:  After giving effect to the Reverse Stock Split, Jeremy C. Green's beneficial ownership of Common Stock is comprised of 630,686 shares of Common Stock owned by the Redmile Funds, including RBI III. Subject to the Beneficial Ownership Blocker, Mr. Green may also be deemed to beneficially own 1,957,432 shares of Common Stock issuable upon exercise of the Warrants. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrant, and a holder of a Warrant does not have the right to exercise the Warrant held by such holder, to the extent that the Beneficial Ownership Blocker applies. The 1,765,303 shares of Common Stock reported as beneficially owned by Mr. Green in this Schedule 13G represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below), which includes 1,134,617 shares of Common Stock that could be issued upon exercise of certain of the Warrants under the Beneficial Ownership Blocker. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. Percentage based on: (i) 16,536,085 shares of Common Stock outstanding, which was calculated based on the amount of shares of Common Stock reported by the Issuer to be outstanding as of May 2, 2025 in the Form 10-Q and taking into account the Reverse Stock Split as reported by the Issuer in the Form 8-K; plus (ii) 1,134,617 shares of Common Stock issuable upon exercise of the Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.


SCHEDULE 13G




Comment for Type of Reporting Person:  After giving effect to the Reverse Stock Split, RBI III's beneficial ownership of Common Stock is comprised of 12,773 shares of Common Stock directly held by RBI III. Subject to the Beneficial Ownership Blocker, RBI III may also be deemed to beneficially own 1,957,432 shares of Common Stock issuable upon exercise of the Warrants directly held by RBI III. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of any Warrant, and a holder of a Warrant does not have the right to exercise any portion of the Warrant held by such holder, if the Beneficial Ownership Blocker applies. The shares of Common Stock reported as beneficially owned by RBI III in this Schedule 13G represent the shares of Common Stock held directly by RBI III and the 1,134,617 shares of Common Stock that could be issued to RBI III upon exercise of certain of the Warrants directly held by RBI III under the Beneficial Ownership Blocker. Percentage based on: (i) 16,536,085 shares of Common Stock outstanding, which was calculated based on the amount of shares of Common Stock reported by the Issuer to be outstanding as of May 2, 2025 in the Form 10-Q and taking into account the Reverse Stock Split as reported by the Issuer in the Form 8-K; plus (ii) 1,134,617 shares of Common Stock issuable upon exercise of the Warrants directly held by RBI III, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.


SCHEDULE 13G



 
Redmile Group, LLC
 
Signature:/s/ Jeremy C. Green
Name/Title:Managing Member
Date:08/14/2025
 
Jeremy C. Green
 
Signature:/s/ Jeremy C. Green
Name/Title:Jeremy C. Green
Date:08/14/2025
 
Redmile Biopharma Investments III, L.P.
 
Signature:/s/ Jeremy C. Green
Name/Title:Managing Member of Redmile Biopharma Investments III (GP), LLC, general partner of Redmile Biopharma Investments III, L.P.
Date:08/14/2025