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Exhibit 21.1

SUBSIDIARIES OF MIAMI INTERNATIONAL HOLDINGS, INC.
(as of December 31, 2025)

Name of SubsidiaryJurisdiction of Organization
Miami International Securities Exchange, LLCDelaware
MIAX PEARL, LLCDelaware
MIAX Emerald, LLCDelaware
MIAX Sapphire, LLCDelaware
Miami International Technologies, LLCDelaware
MIAX Global, LLCDelaware
The International Stock Exchange Group LimitedGuernsey
The International Stock Exchange Authority LimitedGuernsey
The Bermuda Stock ExchangeBermuda
BSD Nominee Ltd.Bermuda
M 9 Holdings, LLCDelaware
MIAX Products, LLCIllinois
MIAX Global Derivatives, LLCDelaware
M 402 Holdings, LLCDelaware
MIAX Futures Exchange, LLCDelaware
M 7 Holdings, LLCDelaware
LedgerX LLC d/b/a MIAX Derivatives ExchangeDelaware
M 8 Holdings, LLCDelaware
Dorman Trading, LLCIllinois
MGEX Real Estate Holdings, LLCDelaware
MIH East Holdings, LimitedEngland and Wales